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Integrin-Associated Focal Adhesion Kinase Protects Human Embryonic Stem Cells...

Vitillo(Loriana),Baxter(Melissa),Iskender(... Stem Cell Reports 0000-00-00

...MDM2, and upregulation of p53, all key players in hESC regulatory networks. Loss of integrin activity or FAK also induce...

MicroRNA-610 is downregulated in glioma cells, and inhibits proliferation and...

Yan(Yu),Peng(Yong),Ou(Yangzhu),Jiang(Yugan... Mol Med Rep 0000-00-00

...MDM2 proto-oncogene E3 ubiquitin protein ligase to function as a tumor suppressor in glioma. These results indicate that...

Pharmacogenetic predictors of toxicity to platinum based chemotherapy in non-...

Pérez-Ramírez(Cristina),Cañadas-Garre(Mari... Pharmacol Res 0000-00-00

...MDM2, ABCB1, MTHFR, MTR, SLC19A1, IL6 and IL16 gene polymorphisms may contribute to individual variation in toxicity to ...

A Functional Polymorphism (rs937283) in the MDM2 Promoter Region is Associate...

Jiao(Yongfa),Jiang(Zhongming),Wu(Yuxia),Ch... Sci Rep 0000-00-00

...MDM2 has been investigated in several cancer types. Three MDM2 SNPs(rs937283, rs2270744 and rs769412) have previously be...

Dual inhibition of protein kinase C and p53-MDM2 or PKC and mTORC1 are novel ...

Carita(Guillaume),Frisch-Dit-Leitz(Estelle... Oncotarget 0000-00-00

...MDM2 inhibitor) and RAD001 (mTORC1 inhibitor) demonstrated greater activity than single agents, with tumor regression ob...

MDM2 Expression in Serous and Mucinous Epithelial Tumours of the Ovary.

Abdelaal(Shereen E),Habib(Fahima M),El Din... Asian Pac J Cancer Prev 0000-00-00

...MDM2 antibody for immunohistochemistry.,MDM2 positivity was detected in 28.9% of the studied ovarian tumours. All benign...

Well-Differentiated Laryngeal/Hypopharyngeal Liposarcoma in the MDM2 Era Repo...

Zhu(Hui),Sun(Jihong),Wei(Shi),Wang(Diping)... Head Neck Pathol 0000-00-00

...MDM2 amplification in liposarcomas at this site.

PRDM1 overexpression induce G0/G1 arrest in DF-1 cell line.

Wan(Zhiyi),Lu(Yanan),Rui(Lei),Yu(Xiaoxue),... Gene 0000-00-00

...MDM2 genes were significantly increased in DF-1 cells transfected with the PRDM1 expression vector. Examination of the R...

Dynamics of ARF regulation that control senescence and cancer.

Ko(Aram),Han(Su Yeon),Song(Jaewhan) BMB Rep 0000-00-00

...MDM2 (a p53 E3 ligase) in the nucleolus, thus activating p53. Besides MDM2, ARF has numerous other interacting partners ...

Prenylated Chalcone 2 Acts as an Antimitotic Agent and Enhances the Chemosens...

Fonseca(Joana),Marques(Sandra),Silva(Patrí... Molecules 0000-00-00

...MDM2 interaction. However, the cellular changes through which PC2 exerts its cytotoxic activity and its antitumor potent...

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