...MDM2. One of them was serendipitously confirmed by biophysical assays and X-ray crystallography to be important for the ...
...Mdm2 were upregulated by luteolin. Conclusion. Luteolin protects H9C2 cells from H2O2-induced apoptosis. The protective ...
...MDM2 and PI3K/AKT as well as NF-κB signaling pathway. In vivo experiments showed that by241 did not have significant acu...
...MDM2 or MDM4, p53 depletion did not rescue the lethality of homozygous mice. The HERC2 protein levels were reduced by ap...
...MDM2), the main p53-suppressor in the cell, inhibiting its function and leading to p53 activation. Here, we discuss the ...
...MDM2 oncoprotein and an intrinsically disordered p53 peptide. A total of 182 independent, continuous binding pathways we...
...Mdm2 and Mdm4 during development suggest that these control mechanisms are context-dependent. Artery formation requires ...
...MDM2 and mTOR while stimulated caspase-3, p53 and GSK3β expression, promoting apoptosis and suppressing proliferation of...
...MDM2. Moreover miR-579-3p ectopic expression impairs the establishment of drug resistance in human melanoma cells. Final...
...Mdm2/p53 and Caspase-3 signaling pathways respectively. In our study, western blot, RT-PCR, immunochemical assay, immuno...
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