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Upregulation of brain expression of P-glycoprotein in MRP2-deficient TR(-) rats…

Hoffmann(K),Löscher(W) Epilepsia 2007-04-00

...Pgp substrate phenobarbital and the selective Pgp inhibitor tariquidar in TR(-) rats substantiated that Pgp is functiona...

Pregnancy-related low back pain and pelvic girdle pain approximately 14 months …

Bergström(Cecilia),Persson(Margareta),Mogren… BMC Pregnancy Childbirth 2014-11-04

...PGP, whereas 65.3% (n = 115) and 15.3% (n = 27), reported recurrent LBP/PGP or continuous LBP/PGP, respectively. The tim...

Effects of the P-glycoprotein (Pgp) antagonist tariquidar (XR-9576; TQD) on Pgp…

Menefee(M E),Huang(H),Edgerly(M),Kotz(H),Mer… J Clin Oncol 0000-00-00

...Pgp inhibition in vivo.,TQD results in potent and sustained inhibition of Pgp. mACC expresses functional Pgp and this ca...

New regional localisations for HAGH and PGP on human chromosome 16.

Mulley(JC),Callen(DF) Hum Genet 1986-12-00

...PGP were present only in cell lines containing human 16p13. This localisation for PGP indirectly places the tightly link...

Drug-drug interactions affected by the transporter protein, P-glycoprotein (ABC…

Aszalos(A) Drug Discov Today 2007-10-00

...Pgp, the induction of Pgp by xenobiotics and the polymorphisms of Pgp related to drug-drug interactions. We also describ...

Distinct poor prognostic subgroups of acute myeloid leukaemia, FLT3-ITD and P-g…

Seedhouse(Claire H),Mills(Ken I),Ahluwalia(S… Leuk Res 2014-02-26

...Pgp) in AML was investigated. In a historical cohort with Pgp and transcriptional regulator expression profiling data av...

Variable p-glycoprotein immunoreactivity unrelated to cytotoxic drug-resistance…

Backlin(C),Fridborg(H),Juhlin(C),Nygren(P),A… Int J Oncol 1994-09-00

...Pgp reactivity demonstrated universally poor sensitivity to 9 standard drugs including those with Pgp mediated resistanc...

Photoaffinity substrates for P-glycoprotein.

Beck(WT),Qian(XD) Biochem Pharmacol 1992-01-09

A variety of compounds can inhibit the function of P-glycoprotein (Pgp) by binding to it and preventing the efflux of an...

Functional expression of a multidrug P-glycoprotein transporter of Leishmania.

Cortés-Selva(F),Muñoz-Martínez(F),Iliás(A),J… Biochem Biophys Res Commun 2005-04-08

P-glycoprotein (Pgp) transporters play an important role in multidrug resistance in eukaryotic cells and in protozoan pa...

Novel Intrinsic Mechanisms of Active Drug Extrusion at the Blood-Brain Barrier:…

Löscher(W),Gericke(B) Pharmaceutics 2020-10-14

...Pgp expression and functionality, novel mechanisms such as intra- and intercellular Pgp trafficking and intracellular Pg...

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