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Future perspectives for the development of P-glycoprotein modulators.

Sandor(V),Fojo(T),Bates(SE) Drug Resist Updat 1998-00-00

...Pgp and related transporters, will form a strong foundation for future research into the role of Pgp and Pgp modulation ...

P-glycoprotein modulation by the designer drugs methylenedioxymethamphetamine, …

Ketabi-Kiyanvash(N),Weiss(J),Haefeli(WE),Mik… Addict Biol 2003-12-00

...Pgp using a fluorometric calcein assay as a model for Pgp inhibition in porcine kidney epithelial cells with overexpress...

Semax and Pro-Gly-Pro activate the transcription of neurotrophins and their rec…

Dmitrieva(VG),Povarova(OV),Skvortsova(VI),Li… Cell Mol Neurobiol 2010-01-00

Consisting of a fragment of ACTH(4-7) and C-terminal PGP tripeptide, the polypeptide Semax is successfully used for acut...

Suppressive effect of tobacco smoke extracts on oral P-glycoprotein function an…

Pan(WC),Chen(RM),Shen(YC),Chen(CC),Ueng(YF) Toxicol Lett 2009-03-10

...Pgp) participates in the export of numerous toxins, drugs, and physiological compounds. To examine the involvement of Pg...

Putative down-stream signaling molecule of GTPase in Porphyromonas gingivalis.

Chun(MJ),Park(KJ),Ohk(SH) Prikl Biokhim Mikrobiol 2012-00-00

...pgp) of this bacterium was cloned and its recombinant protein (rPGP) was produced in Escherichia coli. Based on the amin...

Imaging reversal of multidrug resistance in living mice with bioluminescence: M…

Pichler(A),Prior(JL),Piwnica-Worms(D) Proc Natl Acad Sci U S A 2004-02-10

...Pgp-modulated manner. In Pgp-expressing Rluc cells, low baseline bioluminescence could be fully enhanced (reversed) to n...

Drug resistance and sensitivity of germ cell testicular tumors: evaluation of c…

Eid(H),Géczi(L),Mágori(A),Bodrogi(I),Instito… Anticancer Res 1998-00-00

...Pgp positive tumors is the consequence of Pgp association with a more progressive malignant phenotype, rather than its r...

Strategies to circumvent multidrug resistance due to P-glycoprotein or to alter…

Beck(WT) Bull Cancer 1990-00-00

...Pgp-MDR. However, because inhibition of normal tissue Pgp can cause unacceptable toxicities, new strategies to circumven...

P-glycoprotein deficiency at the blood-brain barrier increases amyloid-beta dep…

Cirrito(JR),Deane(R),Fagan(AM),Spinner(ML),P… J Clin Invest 2005-11-00

...Pgp WT mice. These data establish a direct link between Pgp and Abeta metabolism in vivo and suggest that Pgp activity a...

Differences in P-glycoprotein-170 expression and activity between Crohn's disea…

Yacyshyn(B),Maksymowych(W),Bowen-Yacyshyn(MB) Hum Immunol 1999-08-00

...Pgp-170) cell surface pump. Although the mechanism of action of CsA is complex, we determined that Pgp-170 might be expr...

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