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TP53 BRCA1 CRISPR single-cell cancer

Smith(B),Kasamon(Y L),Miller(C B),Chia(C),... J Clin Oncol 0000-00-00

...mos. Pts were on IM for a median of 37 (13-53) mos prior. 4 of 19 pts had FISH pos as their best previous response (BPR)...

Marcucci(G),Klisovic(R B),Wei(W),Liu(S),Pa... J Clin Oncol 0000-00-00

...mos), 6 had complete remission (CR) and 1 incomplete CR (no disease and incomplete blood count recovery). In cohort II, ...

Maiello(E),Tozzi(L),Latiano(T P),De Bonis(... J Clin Oncol 0000-00-00

19506 Background: GISTs represents 0.1-3% of gastrointestinal neoplasms; most cases occur in people 40 to 80 years old, ...

Manegold(C),Thatcher(N),Kortsik(C),Koschel... J Clin Oncol 0000-00-00

...mos (p=.03) and 6.3/8.6 mos; and median time to progression (TTP) was 4.3/2.2 mos and 2.4/3.3 mos. In S3, CRHT occurred ...

Blackstock(A W),Socinski(M A),Bogart(J),Gu... J Clin Oncol 0000-00-00

...mos, the med PFS is 7.7 mos and the MST is 13.9 mos. There was a correlation between Gr 3-5 pulmonary toxicity and V ≥ 3...

Kawahara(M),Ogawara(M),Nishiwaki(Y),Kubota... J Clin Oncol 0000-00-00

...mos (p=0.95, Log rank), 13.1 vs 13.8 mos (MST, p=0.28, Log rank), 55.6 vs 55.5%, and 27.6 vs 31.8%. Grade 3/4 toxicities...

Alberts(S R),Mahoney(M R),Donohue(J),Roh(M... J Clin Oncol 0000-00-00

...mos of follow-up. 6 deaths occurred in less than 2 yrs. 44% (20/45) have recurred, with 40% (8/20) having liver involvem...

Lind(P A),Larsson(T),Lideståhl(A),Thoren(L... J Clin Oncol 0000-00-00

...mos post-RT FUs. They underwent gadolinium enhanced cardiac MRI and rest-SPECT. The mean cardiac (MCD) and left ventricu...

Fuchs(C),Marshall(J),Mitchell(E),Wierzbick... J Clin Oncol 0000-00-00

...mos) was significantly better than for either m-IFL (6.0 mos; p = 0.01) or CapeIri (5.7 mos; p = 0.01). Overall survival...

Falcone(A),Masi(G),Brunetti(I),Benedetti(G... J Clin Oncol 0000-00-00

...mos, HR: 0.63, p=0.0006; median S 16.7 vs 22.6, HR:0.70, p=0.032).,The FOLFOXIRI regimen is feasible with manageable tox...

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