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Hepatic arterial infusional (HAI) therapy in patients with unresectable prima...

Jarnagin(W R),Schwartz(L H),Gultekin(D H),... J Clin Oncol 0000-00-00

...mos), 1- and 2-year survival was 88% and 68%, respectively; median survival was 29 mos. Two pts with HCC responded (25%)...

Cisplatin-based combination chemotherapy consisting of ifomide, epirubicin, a...

Murakami(F),Ogawa(N),Yamazaki(A),Yamada(M)... J Clin Oncol 0000-00-00

...MOS) for all 40 pts was 24.3 months (mo) (range, 4 to 78). MOS of pts achieving CR, PR, and NC were 'not reached", 23.6 ...

Phase III multicenter web-based study demonstrating survival equivalents of n...

Rigas(J R),Carey(M),Dragnev(K H),Simeone(S... J Clin Oncol 0000-00-00

...mos with 754 deaths. Median survival time (MST) for both treatment groups was 7.9 mos. Non-P arm was non-inferior to the...

A randomized phase II trial of sorafenib versus sorafenib plus low-dose inter...

Tannir(N M),Zurita(A J),Heymach(J V),Tran(... J Clin Oncol 0000-00-00

...mos (95% CI, 5.5- 9.2), compared to 7.6 mos (95% CI, 5.2-11.1) for the combination arm (P=NS). Median OS times were not ...

Phase II trial of cetuximab (C225) in combination with monthly carboplatin (C...

Borghaei(H),Langer(C J),Millenson(M),Tuttl... J Clin Oncol 0000-00-00

...mos; 1 yr OS 53%, 2 yr OS 18%. 13 completed 6 cycles and went onto maintenance therapy with C225 alone. Respective MS fo...

Overall survival with sunitinib versus interferon (IFN)-alfa as first-line tr...

Figlin(R A),Hutson(T E),Tomczak(P),Michael... J Clin Oncol 0000-00-00

...mos vs 5 mos [P<0.000001]). The most common grade 3/4 treatment-related AEs for the sunitinib group are hypertension (12...

Updated results of phase I trial of sorafenib (S) and bevacizumab (B) in pati...

Sosman(J A),Flaherty(K T),Atkins(M B),McDe... J Clin Oncol 0000-00-00

...mos of treatment (TIA, AMI) Pryidoxine did not ameliorate HFS. Only 4/48 pts stopped therapy due to toxicities. MTD was ...

Randomized phase III trial of thalidomide (Th) or placebo (P) for non-metasta...

Figg(W D),Aragon-Ching(J B),Steinberg(S M)... J Clin Oncol 0000-00-00

...mos versus 6.6 mos for the P arm (P=0.0002). Grade 3 or 4 events occurred in ≤5% of pts on Th. Most common grade 2 toxic...

Use of prostate-specific antigen progression (PSA-P) to predict overall survi...

Hussain(M H),Goldman(B),Tangen(C M),Higano... J Clin Oncol 0000-00-00

...mos for pts who did or did not have PSA-P by 3 mos.,PSA-P defined as an increase of ≥ 25% over baseline or nadir with an...

Preliminary results of a randomized phase II trial of pemetrexed (P) + carbop...

Kocs(D M),Raju(R N),Socinski(M A),Stinchco... J Clin Oncol 0000-00-00

...mos vs. 10.1 mos for vinorelbine + C (P=.04). This open-label three-arm trial was designed to assess PCb ± ENZ versus a ...

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