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Effective TRAIL-based immunotherapy requires both plasmacytoid and CD8α dendr...

James(Britnie R),Brincks(Erik L),Kucaba(Ta... Cancer Immunol Immunother 2014-09-30

...Batf3(-/-) BALB/c mice) had uncontrolled tumor growth and high mortality after Ad5-TRAIL/CpG administration. The ineffec...

Batf3 and Id2 have a synergistic effect on Irf8-directed classical CD8α+ dend...

Jaiswal(Hemant),Kaushik(Monika),Sougrat(Ra... J Immunol 2014-02-18

...Batf3 was not sufficient for directing classical CD8α(+) DC development. When coexpressed with Irf8, Batf3 and Id2 had a...

Central role of conventional dendritic cells in regulation of bone marrow rel...

Jiao(Jingjing),Dragomir(Ana-Cristina),Koca... J Immunol 2014-06-09

...Batf3 knockout mice, which have defects in DC development, have increased numbers of liver neutrophils in the steady sta...

Ontogenic, Phenotypic, and Functional Characterization of XCR1(+) Dendritic C...

Becker(Martina),Güttler(Steffen),Bachem(An... Front Immunol 2014-08-14

...Batf3. XCR1(+) DC are located in the villi of the lamina propria of the small intestine, the T cell zones of Peyer's pat...

Effective treatment of allergic airway inflammation with Helicobacter pylori ...

Engler(Daniela B),Reuter(Sebastian),van Wi... Proc Natl Acad Sci U S A 2014-10-20

...BATF3)-dependent CD103(+)CD11b(-) dendritic cell lineage is enriched in the lungs of protected mice and strictly require...

Distinct contributions of Aire and antigen-presenting-cell subsets to the gen...

Perry(Justin S A),Lio(Chan-Wang J),Kau(And... Immunity 2014-11-18

...Batf3-dependent CD8α⁺ dendritic cells (DCs) were the crucial BM APCs for Treg cell selection via this pathway, showing e...

Identification of immune factors regulating antitumor immunity using polymeri...

Ali(Omar A),Verbeke(Catia),Johnson(Chris),... Cancer Res 2014-05-08

...Batf3(-/-) mice revealed that CD8(+) DCs are required to affect tumor protection, as vaccines in these mice were deficie...

Cross-presenting dendritic cells are required for control of Leishmania major...

Ashok(Devika),Schuster(Steffen),Ronet(Cath... Eur J Immunol 2014-06-09

...Batf3(-/-) ) mice (C57BL/6 background) that lack the major IL-12 producing and cross-presenting CD8α(+) and CD103(+) DC ...

Specificity through cooperation: BATF-IRF interactions control immune-regulat...

Murphy(Theresa L),Tussiwand(Roxane),Murphy... Nat Rev Immunol 2013-12-11

Basic leucine zipper transcription factor ATF-like (BATF), BATF2 and BATF3 belong to the activator protein 1 (AP-1) fami...

Intestinal lamina propria dendritic cells maintain T cell homeostasis but do ...

Welty(Nathan E),Staley(Christopher),Ghilar... J Exp Med 2013-11-19

...BatF3(-/-) mice lacked both CD103(+) LP DC subsets, resulting in defective gut homing and fewer LP T reg cells. Despite ...

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