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Therapeutic effects of Icariside II on radiation cystitis: revealing the mech...

Sun(J),Wang(W),Li(H),Yan(Y),Pan(X),Liu(Y),... Int J Surg 2026-07-00

...FN1 expression was markedly upregulated following radiation exposure. FN1 binds to its receptor Itgαvβ6, activating the ...

Multi-omics, machine learning, and molecular simulation identify CD44 as a ca...

Hu(Y),Liu(K),Chen(T),He(Z),Li(S),Hu(W),Fu(... Mol Divers 2026-08-30

...FN1, BCL2, CD44, CDKN1A, CTNNB1, and JUN. The Lasso + LDA model achieved an average AUC of 0.976 across the training coh...

Single-cell and spatial transcriptomics characterisation of RSPO2+ nucleus pu...

Li(Q),Liang(G),Bo(K),Kang(L),Jin(P),Zhao(C... J Orthop Translat 2026-09-00

...FN1-CD44 signalling scores increased across expanded degenerative effector populations. Human panels were used as repres...

Integrative Single-Cell and Spatial Transcriptomics Identifies CRIP1+ Prehype...

Xie(Z),Wang(Y),Liu(J),Li(H),Bian(H),Gu(C) Mediators Inflamm None

...FN1 signaling pathway. Spatial transcriptomics confirmed that CRIP1+ preHTC co-localizes with prefibroblasts (preFC) in ...

Integrated Analysis of Multiple Databases Identifies Tissue Inhibitor of Meta...

Xie(Y),Li(J),Yan(Z),Zhang(W) Genes (Basel) 2026-08-20

...FN1, PRG4, and a cluster of nine MMPs (MMP1/2/3/7/8/9/11/13/14), all of which showed significant positive correlations w...

Effect of Plasma Gel on Viability, Proliferation and Migration of Dermal Huma...

Slompo(C),Carvalho(EP),Silva(TKD),Roldan(B... Gels 2026-08-12

...FN1 was performed after 24, 48, and 72 h. Fibroblasts cultured with plasma gel from G3 and G4 showed significantly highe...

Computational identification and experimental validation of shared diagnostic...

Zhu(X),Liang(C),Xu(Z),Zhao(X),Shi(L),He(J)... J Transl Med 2026-08-29

...FN1, F2R, HIF1A, ANGPT2). Immune infiltration profiles varied significantly across diseases. Regulatory network analysis...

Integrated Single-Cell and Spatial Transcriptomics Reveal SERPINE1 as a Key L...

Yu(H),Wu(J),Hong(Q),Lin(H),Li(Y),Chen(D),W... Biofactors 2026-00-00

...FN1, LAMININ, and SPP1 pathways. Five macrophage subclusters were resolved. Among them, macro_SPP1 and macro_IL1B signat...

An hiPSC-derived multi-lineage lung model exhibiting proximal-distal epitheli...

Hua(C),Qu(C),Yang(L),Zhao(W),Zhao(J),Jia(Y... Front Cell Dev Biol 2026-00-00

...FN1, and integrin family members as central hubs. Bidirectional GSEA validation confirmed that the transcriptomic signat...

Fibronectin Is a Likely Therapeutic Target Shared by Oral and Breast Carcinomas.

Pomella(S),Bei(R),Melaiu(O),Barillari(G) Int J Mol Sci 2026-01-23

...FN1 gene coding for the extracellular matrix glycoprotein fibronectin (FN) emerged as the EMT gene common to either tumo...

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