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Sulfate biology genes are associated with mineralization in mouse and human.

Lee(KD),Dawson(PA),Summers(KM) JBMR Plus 2025-10-00

...Got1, and Sulf1) were upregulated in Saos-2 mineralization but downregulated in mouse primary osteoblasts. Cbs, Chst3, a...

Cold-inducible GOT1 activates the malate-aspartate shuttle in brown adipose tis…

Park(CH),Park(M),Kelly(ME),Cheng(H),Lee(SR),… Cell Rep 2025-07-22

...GOT1), a key MAS enzyme, via the β-adrenergic receptor-PKA-PGC-1α axis. The increase in GOT1 activates MAS, transferring...

FAK inhibition disrupts tumor growth, apoptosis, and transcriptional regulation…

Toffoli(L),Ditsiou(A),Triboli(L),Hamm(V),Mos… Endocr Oncol 2025-01-00

...GOT1 and COLO320DM) were treated with Y15, a kinase inhibitor, and PROTAC-FAK (BI-0319), a degrader that abrogates both ...

Exploring the multifaceted roles of glutamate oxaloacetate transaminase 1 as a …

Wang(X),Pi(L),Chen(Y),Tan(J),Wang(Y),Xia(K),… Discov Oncol 2025-08-23

...GOT1 with CRC. GOT1 expression significantly varied across cancer types, showing high diagnostic value in colon adenocar...

BDH1 acetylation at K116 modulates milk fat production in dairy goats.

Xiong(T),Chen(C),Gong(X),Han(C),Tian(M),Luo(… Res Sq 2025-07-29

...GOT1, GOT2, BDH1, ACSS1, STAT5B, FABP5, and GPAM were identified as candidates potentially involved in milk protein synt...

Comprehensive genotypic, phenotypic, and biochemical characterization of GOT2 d…

German(HM),Zaki(MS),Usmani(MA),Karagoz(I),Ef… Genet Med 2025-12-00

...GOT1) and mitochondrial (GOT2), are integral to the malate-aspartate shuttle, a key regulator of intracellular redox hom...

African swine fever virus hijacks host pyrimidine metabolism to promote viral r…

Song(Z),Chen(Y),Guo(H),Zhang(G),Gong(L),Zhen… J Virol 2025-11-25

...GOT1-mediated synthesis pathway. Collectively, these findings elucidate how ASFV reprograms host nucleotide metabolism t...

Can the Quality of Semen Affect the Fertilisation Indices of Turkey Eggs?

Orzołek(A),Dziekońska(A),Skorynko(P),Ner-Klu… Int J Mol Sci 2025-11-13

...GOT1), and L-lactate dehydrogenase B (LDHB) were detected only in IF semen. Overall, the results demonstrate that both s...

Immunomodulatory effects and mechanisms of Qi-Xu-Tiao-Ti formula in Qi-deficien…

Cui(R),Fan(M),Yang(C),Chen(C),Xia(J),Liu(X),… Front Immunol 2025-00-00

...GOT1, SLC16A8, FTCD, ERBB2, GSS, VLDLR, and IL2. Functional enrichment analysis revealed significant overrepresentation ...

Expression, purification and preliminary crystallographic studies of human glut…

Jiang(Xiuping),Chang(Haiyang),Zhou(Yong) Protein Expr Purif 2016-02-19

...GOT1 and GOT2, respectively. GOT1 expression correlates with the growth of several tumors because cancer cells can utili...

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