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[Mechanism of expression of the Src family kinases (Fgr, Hck, Lyn) and SSeCKS i…

Zhang(LingYan),Shao(Jianguo),Xiao(Feng),Chen… Zhonghua Gan Zang Bing Za Zhi 2016-02-13

...Hck, Fgr, Lyn were detected by immunohistochemical staining.,Expression of Lyn and Hck was decreased in the CCL4-stimula...

A critical role of Src family kinase in SDF-1/CXCR4-mediated bone-marrow progen…

Cheng(Min),Huang(Kai),Zhou(Junlan),Yan(Dewen… J Mol Cell Cardiol 2016-03-02

...Hck) in WT cells but not in AMD3100-treated cells or CXCR4-KO cells. Then, we investigated whether SFK are involved in S...

The Neutrophil Btk Signalosome Regulates Integrin Activation during Sterile Inf…

Volmering(Stephanie),Block(Helena),Boras(Mar… Immunity 2016-06-07

...Hck, Wiskott-Aldrich-syndrome protein, and phospholipase Cγ2 were also involved in this pathway required for fMLF-trigge...

Src is required for migration, phagocytosis, and interferon beta production in …

Maa(Ming-Chei),Leu(Tzeng-Horng) Biomedicine (Taipei) 2016-08-12

...Hck, and Lyn are myeloid-specific Src family kinases. Despite their constitutively high expression in macrophages, their...

Prolactin-induced protein (PIP) regulates proliferation of luminal A type breas…

Baniwal(Sanjeev K),Chimge(Nyam-Osor),Jordan(… PLoS One 2015-01-28

...HCK). Ablation of PIP also abrogated serum-induced activation of the downstream serine/threonine kinases AKT, ERK1/2, an...

The inhibition of SRC family kinase suppresses pancreatic cancer cell prolifera…

Je(Dong Wook),O(Young Moon),Ji(Young Geon),C… Pancreas 2015-02-07

...Hck, and Src were expressed. Specific small interfering RNA transfection suppressed the messenger RNA expressions of Yes...

An efficient siRNA-mediated gene silencing in primary human monocytes, dendriti…

Troegeler(Anthony),Lastrucci(Claire),Duval(C… Immunol Cell Biol 2015-05-25

...Hck) shows for the first time that this kinase regulates the protease-dependent migration mode in human monocytes. Colle...

Node interference and robustness: performing virtual knock-out experiments on b…

Scardoni(Giovanni),Montresor(Alessio),Tosado… PLoS One 2015-01-02

...HCK, FGR and JAK2, are predicted by the interference and robustness analysis, are in agreement with previous studies and...

Hck/Fgr Kinase Deficiency Reduces Plaque Growth and Stability by Blunting Monoc…

Medina(Indira),Cougoule(Céline),Drechsler(Ma… Circulation 2015-11-02

...Hck and Fgr are instrumental in this process, their impact on atherosclerosis and on lesion inflammation and stability w...

HIV-1 reprograms the migration of macrophages.

Vérollet(Christel),Souriant(Shanti),Bonnaud(… Blood 2015-04-27

...Hck and Wiskott-Aldrich syndrome protein (WASP), 2 major regulators of podosomes. In conclusion, HIV-1 reprograms macrop...

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