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Concurrent initiation of treadmill exercise protects against angiotensin II-i...

Baek(KW),Won(JH),Xiang(YY),Woo(DK),Park(Y)... J Physiol Biochem 2026-02-18

...Jun N-terminal kinase [JNK]), and autophagy (microtubule-associated protein 1 light chain 3 beta [LC3B], sequestosome [p...

The basic helix-loop-helix transcription factor TCF4 recruits the Mediator co...

O'Neil(EV),Dupont(SM),Liang(H),Singh(R),Ca... Genes Dev 2026-08-03

...Jun and Fos In ex vivo gonad culture, inhibition of JUN activation led to decreased Wnt4 expression. These results suppo...

Elucidating the mechanism of Buyang Huanwu Decoction in the treatment of isch...

Shi(T),Chen(Z),Wang(M),Chen(D) Medicine (Baltimore) 2026-07-17

...Jun proto-oncogene, AKT serine/threonine kinase 1, mitogen-activated protein kinase 1, and estrogen receptor alpha. The ...

Integration of network toxicology, machine learning and single-cell sequencin...

Yang(L),Qing(X),Wang(J) Discov Oncol 2026-07-19

...JUN (AUC = 0.733), all validated across cohorts. scRNA-seq module scoring showed the highest activity in T cells, monocy...

Identification of Potential Core Genes in Medication-Related Osteonecrosis of...

Duan(X),Bian(Y),Han(S),Shen(J),Yuan(Y),Fan... Oral Dis 2026-07-19

...JUN, CXCL8, CXCR4, PTPRC, IL1A, HSP90AB1, RHOA) were identified. Four of them (HSP90AB1, RHOA, CXCL8, IL1B) showed high ...

Quercetin as the core constituent of Huanglian decoction: Targeting AKT1 for ...

Ye(Y),Wang(X),Xu(X) Pak J Pharm Sci 2026-10-00

...JUN, IL6, MYC, FOS and CCND1. Quercetin was identified as a core active compound of HD, which likely exerts its effects ...

A Network Pharmacology and Molecular Docking Study of TongBi Formula for Oste...

Liang(R),Zhang(W),Xiong(J),Peng(Y),Hu(J) J Vis Exp 2026-07-03

...JUN, RELA, IL6, MAPK1, and IL10 as potential hub targets. Enrichment analysis suggested that TBF may regulate inflammati...

All-trans retinoic acid suppresses systemic inflammation induced by severe fe...

Yu(X),Wu(J),Yin(X),Yue(M),Zhang(Y),Meng(J)... Nat Microbiol 2026-08-00

...JUN and suppresses the expression of AP-1 promoter-dependent genes, such as IL-6, thus attenuating inflammatory signalli...

IL-17-associated Pro-inflammatory Programs in Aortic Valve Interstitial Cell ...

Dai(Y),Kong(S),Yang(Y),Zhang(Y),He(Y),He(P... Inflammation 2026-07-21

...JUN silencing attenuated calcification. IL-17 A rapidly increased the p-c-JUN/JUN ratio, and prolonged treatment upregul...

Multi-omics analysis suggests a potential role of the complement-coagulation ...

Yang(L),Zhang(N),Dai(H),Dong(Z),Liu(W),Liu... Int Urol Nephrol 2026-07-21

...JUN, and TIMP1) were prioritized. Among them, C3AR1 was closely associated with monocyte-related signatures and was posi...

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