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Lung Cancer Driver Mutations in Middle Eastern Americans: Associations with S...

Henderson(A),Zheng(AM),Daraiseh(S),Khayyat... Avicenna J Med 2026-01-00

...KRAS, EGFR, ALK, BRAF, and MET were identified using targeted NGS panels. Smoking exposure and duration of U.S. residenc...

Key Considerations for Targeting KRAS in Pancreatic Cancer: Potential Impact ...

Eslinger(C),Sonbol(MB),George(B),Babiker(H... Drug Des Devel Ther None

...KRAS as the dominant oncogenic driver in PDAC. Long considered undruggable, KRAS has recently become a viable therapeuti...

[Algorithms for the diagnosis of lung tumors].

Forest(F) Ann Pathol 2026-03-31

...KRAS, STK11, and KEAP1mutation testing. Finally, clones of these antibodies can show different results in terms of sensi...

Endometrioid Versus Seromucinous Borderline Ovarian Tumors: Divergent Molecul...

Niu(S),Molberg(K),Carrick(K),Colon(GR),Gwi... Int J Gynecol Pathol 2026-07-01

...KRAS (36%), ARID1A (27%), ATR (27%), KMT2D (27%), PIK3CA (18%), PIK3R1 (18%), PTEN (18%), AKT1 (18%), TP53 (18%), and se...

An ultrasensitive fluorescent strategy based on ligation-promoted exponential...

Huang(F),Du(Q),Yu(R),Chen(H),Huang(Y),Han(... Spectrochim Acta A Mol Biom... 2026-09-05

...KRAS sequence based on Bsu DNA polymerase inserting adenine opposite 8-oxoG. And then EXPAR could proceed along with the...

Clinicogenomic Predictors of First-line Immune Checkpoint Inhibitor Outcomes ...

Iwasaki(M),Ando(T),Fujii(K),Watanabe(K),Od... Clin Lung Cancer 2026-05-00

...KRAS, KEAP1, and STK11, with genes from exploratory screening. We tested KRAS-KEAP1 and KRAS-STK11 interactions. Sensiti...

Computational-experimental repurposing reveals synergistic sorafenib/hydroxyc...

Abdelwahab(MM),Soliman(M),Nassrallah(A) BMC Pharmacol Toxicol 2026-04-02

BACKGROUND: KRAS mutations are approximately 25% of human cancers, with particularly high incidence in breast and lung c...

Integrative Genomic, Transcriptomic, and Microbiome Profiles of Colon Cancer ...

Kramer(M),Belleau(P),Tortora(SC),Deschenes... medRxiv 2026-03-28

...KRAS variants in AFR tumors. Colon cancer genomes in patients in this study also exhibit distinct patterns of DNA copy n...

Multi-omics and experimental validation identify USP54 as a prognostic deubiq...

Yuan(Z),Yu(Z),Xu(Q),Huang(D),Cui(D) Front Immunol None

...KRAS signaling within specific tumor niches adjacent to THBS1-enriched immune regions. High USP54 expression was frequen...

Glutamic Acid-Chelated Cobalt Stabilizes G-Quadruplexes and Selectively Suppr...

Lin(KH),Lin(YJ),Hong(YB),Hsu(MH),Liao(ZX),... Oncol Res None

...KRAS promoter G4 DNA polymerase stop assay, BG4 immunofluorescence, and KRAS qPCR. PRS was used to optimize GACC-metform...

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