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Monozygotic twins discordant for constitutive BRCA1 promoter methylation, chi...

Galetzka(Danuta),Hansmann(Tamara),El Hajj(... Epigenetics 2012-10-22

...RSPO3 gene in the affected twin. This monozygotic twin pair represents an impressive example of epigenetic somatic mosai...

Atlas of Wnt and R-spondin gene expression in the developing male mouse lower...

Mehta(Vatsal),Abler(Lisa L),Keil(Kimberly ... Dev Dyn 2012-03-16

...Rspo3 mRNAs. These results reveal sexual differences in WNT/β-catenin signaling in fetal LUT, supporting the idea that t...

Genome-wide association study using extreme truncate selection identifies nov...

Duncan(Emma L),Danoy(Patrick),Kemp(John P)... PLoS Genet 2011-08-12

...RSPO3, and SOX4, with replication in two independent datasets. A novel mouse model with a loss-of-function mutation in G...

Rspo3 binds syndecan 4 and induces Wnt/PCP signaling via clathrin-mediated en...

Ohkawara(Bisei),Glinka(Andrei),Niehrs(Chri... Dev Cell 2011-05-12

...Rspo3 binds syndecan 4 (Sdc4) and that together they activate Wnt/PCP signaling. In Xenopus embryos, Sdc4 and Rspo3 are ...

A WNT/beta-catenin signaling activator, R-spondin, plays positive regulatory ...

Han(Xiang Hua),Jin(Yong-Ri),Seto(Marianne)... J Biol Chem 2011-06-09

...Rspo3 gene knockdown by RNA interference significantly compromised MYF5 expression, myogenic differentiation, and myotub...

Large-scale genome-wide association studies in East Asians identify new genet...

Kim(Young Jin),Go(Min Jin),Hu(Cheng),Hong(... Nat Genet 2011-11-21

...RSPO3) for renal traits, and 12q24.11 (near MYL2), 12q24.13 (in C12orf51 and near OAS1), 4q31.22 (in ZNF827) and 7q11.23...

Chromosomal assignment of R-spondin genes in the donkey (Equus asinus, 2n = 62).

De Lorenzi(L),Genualdo(V),Perucatti(A),Pia... J Appl Genet 2011-03-02

...RSPO3 on EAS 24q26, and RSPO4 on EAS 15p13. Moreover, RSPO2, RSPO3, and RSPO4 are the first genes mapped on donkey chrom...

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reve...

Heid(Iris M),Jackson(Anne U),Randall(Joshu... Nat Genet 2010-11-16

...RSPO3, VEGFA, TBX15-WARS2, NFE2L3, GRB14, DNM3-PIGC, ITPR2-SSPN, LY86, HOXC13, ADAMTS9, ZNRF3-KREMEN1, NISCH-STAB1 and C...

The Wnt signaling regulator R-spondin 3 promotes angioblast and vascular deve...

Kazanskaya(Olga),Ohkawara(Bisei),Heroult(M... Development 2009-02-03

...Rspo3 induces vascular defects because Rspo3 is essential for regulating the balance between angioblast and blood cell s...

Molecular stages of rapid and uniform neuralization of human embryonic stem c...

Bajpai(R),Coppola(G),Kaul(M),Talantova(M),... Cell Death Differ 2009-07-17

...RSPO3. Concordantly, we never detected tumors or excessive neural proliferation after transplantation of C-NPCs into mou...

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