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sox17 mutagenesis reveals microglia can be impacted by genetic maternal effects.

Hoover(CA),Dennen(J),Gan(D),Li(J),Smith(CJ) bioRxiv 2025-07-31

...sox17 is expressed in microglia and their yolk sac precursors and is maternally-loaded. We show that sox17 restoration v...

Molecular and Genetic Pathogenesis of Oral Cancer: A Basis for Customized Diagn…

Barroso(L),Veiga(P),Melo(JB),Carreira(IM),Ri… Biology (Basel) 2025-07-10

...SOX17, GATA4, ECAD, MGMT, and DAPK. Several microRNAs are upregulated in oral cancer, including miR-21, miR-24, miR-31, ...

SOX17 Regulates Nestin/p16INK4a Axis to Mitigate Endothelial Senescence in Pulm…

Sun(W),Wu(T),Zhou(Z),Jiang(D),Wei(TY),Han(SY… Res Sq 2025-07-29

...SOX17 overexpressing PAECs exacerbated PAEC senescence and worsened PAH in rodents. Our findings reveal a novel SOX17-Ne...

Screening industrial chemicals for human developmental toxicity in the DevTox G…

Gamble(JT),Rogers(J),Breaux(K),Feshuk(M),Thu… Toxicology 2025-11-00

...SOX17 assay endpoint. For the test chemical set, 60 of the 165 chemicals analyzed were active, with 29 exhibiting a degr...

SOX17 in pulmonary arterial hypertension: from development to clinical phenotyp…

Lacoste-Palasset(T),Aguado(B),Grynblat(J),Co… Eur Respir Rev 2025-07-00

...SOX17 (SRY-box transcription factor 17) associated with PAH onset. SOX17, a member of the Sry-related high-mobility grou...

Sox17 mediates venous adaptive remodeling after arteriovenous fistula creation.

Aoyagi(Y),Schwartz(AW),Li(Z),Bai(H),Ho(B),La… JVS Vasc Sci 2025-00-00

...Sox17 expression was localized to the nucleus of EC. Sox17 knockdown mice had impaired venous remodeling, characterized ...

Functionally Essential and Structurally Diverse: Insights into the zebrafish Le…

Ononiwu(F),Mikolaj(M),Dell(C),Shamil(AW),Nar… bioRxiv 2025-09-09

...sox17:Cry2-GFP), we optogenetically disrupted the intraflagellar transport protein IFT88 in KV progenitors via blue ligh...

SOX17: a new therapeutic target for immune evasion of colorectal cancer.

Das(A),Yilmaz(O),Yilmaz(O),Deshpande(V) J Clin Pathol 2025-09-18

...SOX17 could be a promising marker in personalised therapy. Additionally, SOX17 could play a role in the diagnostic arena...

Deficiency of DAZ genes links testicular germ cell tumorigenesis and infertilit…

Chen(J),Li(C),Qiu(S),Zhu(W),He(X),Gao(D),Che… Am J Cancer Res 2025-00-00

...SOX17, BLIMP1, and TFAP2C, accompanied by S-phase shortening, cell cycle dysregulation, and increased apoptosis. RNA seq...

Integrative Bioinformatics-Guided Analysis of Glomerular Transcriptome Implicat…

Yang(T),Dai(M),Zhang(F),Wen(W) Bioengineering (Basel) 2025-09-27

...SOX17). The AUC values for identifying IgAN in the training and testing set ranged from 0.956 to 0.995. Immune infiltrat...

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