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TEAD transcription factors are required for normal primary myoblast differentia…

Joshi(S),Davidson(G),Le Gras(S),Watanabe(S),… PLoS Genet 2017-00-00

...Tead4, Myod1 or Myog. Tead4 regulated distinct gene sets in C2C12 cells and PMs involving both activation of the myogeni...

NT5DC2 promotes leiomyosarcoma tumour cell growth via stabilizing unpalmitoylat…

Hu(B),Zhou(S),Hu(X),Zhang(H),Lan(X),Li(M),Wa… J Cell Mol Med 2021-05-16

...TEAD4, and this association reduced TEAD4 degradation via the ubiquitin-proteasome pathway. TRIM27 is a novel E3 ubiquit...

The role of TEAD4 gene in the Hippo signaling pathway in triple-negative breast…

Zhang(X),Wang(T),Lian(X),Wei(C),Yan(D),Liang… BMC Med Genomics 2025-10-30

...TEAD4, WWTR1, AREG, and SOX11. TEAD4 was confirmed as the central gene influencing TNBC progression. Immunohistochemical...

High YAP and TEAD4 immunolabelings are associated with poor prognosis in patien…

Kim(JY),Sung(YN),Hong(SM) APMIS 2021-12-00

...TEAD4 immunolabeling (p < 0.001). High immunolabeling levels of YAP or TEAD4 alone and the combined YAPhigh TEAD4high gr...

TEAD4 regulates trophectoderm differentiation upstream of CDX2 in a GATA3-indep…

Stamatiadis(P),Cosemans(G),Boel(A),Menten(B)… Hum Reprod 2022-07-30

...Tead4-targeting (previously shown to be expressed downstream of Tead4). Additional groups of gRNA1 Tead4-targeted (n = 4...

TEAD4 transcriptional regulates SERPINB3/4 and affect crosstalk between keratin…

Ren(C),Liu(Q),Ma(Y),Wang(A),Yang(Y),Wang(D) Immunobiology 2020-00-00

...TEAD4 in psoriasis and its possible regulatory mechanism. In this study, we found the expression level of TEAD4 in the s...

PARP1-mediated PARylation of TEAD4 stabilizes the YAP1-TEAD4 complex and promot…

Guo(Y),Song(G),Zou(H),Lu(L),Dai(X),Sun(C),Ch… Sci Signal 2025-10-21

...TEAD4 complex by PARylating TEAD4 at a conserved Arg-Lys sequence. This PARP1-enhanced YAP1-TEAD4 binding attenuated the...

The TEA domain family transcription factor TEAD4 represses murine adipogenesis …

Zhang(W),Xu(J),Li(J),Guo(T),Jiang(D),Feng(X)… J Biol Chem 2018-00-02

...TEAD4 and CtBP2, and this TEAD4-VGLL4-CtBP2 ternary complex dynamically existed at the early stage of adipogenesis. Fina...

VGLL4-driven TEAD4 multimerization orchestrates DNA binding and YAP recruitment.

Ren(Z),Zhao(Y),Yu(W),Zhang(X),Song(X),Bao(Y)… Nat Commun 2026-04-11

...TEAD4: A low VGLL4:TEAD4 molar ratio enhances this process, whereas a high ratio inhibits it. These findings offer a dyn...

Arginine is an epigenetic regulator targeting TEAD4 to modulate OXPHOS in prost…

Chen(CL),Hsu(SC),Chung(TY),Chu(CY),Wang(HJ),… Nat Commun 2021-00-23

...TEAD4 recruitment. Silencing of TEAD4 suppresses OXPHOS functions and prostate cancer cell growth in vitro and in vivo. ...

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