...COL1A1/COL1A2/COL3A1; STAT1; LEF1; CXCR4/IGHG3). Enrichment analyses highlighted immune interferon and TNFα/NFκB signali...
...COL1A1, COL1A2, COL3A1, all p < 0.001) and EMT-related factors (ZFP36, KLF2, NR4A1, all p < 0.001). Co-localization of C...
...COL1A1; loss of YTHDF1 reduced COL1A1 protein levels without affecting its mRNA abundance. Rescue experiments in which C...
...COL1A1, COL3A1, TNMD, TNC, BGN, and SMAD3), morphological alterations (Giemsa staining), metabolic activity (ATP test), ...
...COL1A1, and MMPs, cell proliferation, inflammatory cytokine levels, and reactive oxygen species (ROS) were measured to a...
...COL1A1+_FIB) and mesenchymal (POSTN+_FIB) fibroblast subpopulations. Pseudotime trajectory analysis further revealed tha...
...COL1A1, COL1A2, COL3A1, COL5A1, COL5A2, SPARC, LOX, and LOXL2, indicating reinforced matrix deposition and crosslinking....
...Col1a1: 1.82 ± 0.09 vs. 1.00 ± 0.10; Nfkb1: 1.33 ± 0.03 vs 1.00 ± 0.04; n = 6-10; p < 0.05). In summary, cardiac co-over...
...COL1A1) while inhibiting NF-κB signaling, whereas IL-38 knockdown produced the opposite effects. Notably, Bay11-7082 tre...
...COL1A1 in fibroblasts. This effect was blocked by KLF6 knockdown or TGF-β receptor inhibition. Animal experiments confir...
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