...COL1A1 and DYNC2H1 emerged as the most frequently shared genes. WES provides a substantial incremental yield (19.3%, 95%...
...COL1A1, consistent with activation of early chondrogenic differentiation pathways. Among the tested systems, LK-HAC18L e...
...COL1A1 and COL1A2 account for 85-90% of osteogenesis imperfecta (OI). Glycine substitutions within the triple-helical do...
...Col1a1, Vim, and Timp1. In human MASH liver tissue sections, αvβ6 expression and autoradiographic signals also increased...
...COL1A1), bone gamma-carboxyglutamate protein (BGLAP), and vascular endothelial growth factor A (VEGFA) are consistently ...
...COL1A1 (c.441delC; p.Gly148fs*117), confirming OI, and a heterozygous CYP11A1 variant of uncertain significance (c.119 T...
...COL1A1, COL3A1, and FGF2, and downregulation of IL-1β and MMP-2, indicating profound wound healing activity. In the in o...
...COL1A1 and α-SMA. Histology mirrored these improvements: necrosis, inflammation, and collagen accumulation were diminish...
...COL1A1 levels, and decreased MMP1 levels. Sauchinone also alleviated oxidative stress by reducing intracellular ROS and ...
...COL1A1, reduced MMP2, reinstated TIMP2, and improved collagen density and alignment, thereby mitigating axial elongation...
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