主页文献库搜索
P-glycoprotein and breast cancer resistance protein affect disposition of tan...

Yang(Johnny J),Milton(Mark N),Yu(Shaoxia),... Drug Metab Lett 2011-04-04

...Bcrp1(-/-), and Mdr1a/b(-/-)/Bcrp1(-/-) mice was higher than in the WT mice. The brain to plasma exposure ratio (B/P) of...

Anticancer effects of the nitric oxide-modified saquinavir derivative saquina...

Rothweiler(Florian),Michaelis(Martin),Brau... Neoplasia 2011-03-31

...BCRP1 affected anticancer activity of saq-NO or saquinavir. Moreover, saq-NO sensitized P-gp-, MRP1-, or BCRP1-expressin...

Breast cancer-resistance protein (BCRP1) in the fetal mouse brain: developmen...

Petropoulos(Sophie),Gibb(William),Matthews... Biol Reprod 2011-08-09

...BCRP1 substrates; however, the developmental expression, function, and regulation of Abcg2/BCRP1 in the mouse fetal brai...

Preclinical absorption, distribution, metabolism, excretion, and pharmacokine...

Liederer(Bianca M),Berezhkovskiy(Leonid M)... Xenobiotica 2011-05-19

...Bcrp1 cells suggested that GNE-A is likely a substrate for MDR1 and BCRP. Pharmacokinetic-pharmacodynamic modelling of t...

The bioflavonoid kaempferol is an Abcg2 substrate and inhibits Abcg2-mediated...

An(Guohua),Gallegos(Jorge),Morris(Marilyn ... Drug Metab Dispos 2011-06-14

...Bcrp1 cells, indicating that kaempferol is a Bcrp inhibitor. The intracellular concentration of kaempferol was significa...

[Research of the characterization of Bcrp1(+) HeLa cells].

Zhang(Song-ling),Yu(Xiao-Wei),Wei(Zhen-ton... Zhonghua Fu Chan Ke Za Zhi 2011-08-15

...Bcrp1(+) cells and 92.9% Bcrp1(-)cells in HeLa cells. Bcrp1(+) HeLa cells were large in size of nuclear and nucleoli are...

The role of the breast cancer resistance protein (ABCG2) in the distribution ...

Agarwal(Sagar),Sane(Ramola),Ohlfest(John R... J Pharmacol Exp Ther 2011-01-18

...Bcrp1(-/-) mice, 0.11 ± 0.021 in the Mdr1a/b(-/-) mice, and 0.91 ± 0.29 in the Mdr1a/b(-/-)Bcrp1(-/-) mice compared with...

Radiosynthesis and in vivo evaluation of 1-[18F]fluoroelacridar as a positron...

Dörner(Bernd),Kuntner(Claudia),Bankstahl(J... Bioorg Med Chem 2011-10-24

...Bcrp1((-/-)) mice (n=3). In PET experiments in rats, administration of unlabelled 1 increased brain activity uptake by a...

[Expressions of ATP binding cassette transporter genes in rat hepatic oval ce...

Zhang(Feng),Chen(Xiao-ping),Jing(Kai),Zhan... Zhonghua Gan Zang Bing Za Z... 2010-07-06

...Bcrp1, in isolated hepatic oval cells and hepatocytes were measured by quantitative real-time reverse transcription-poly...

Effect of pregnancy on nitrofurantoin disposition in mice.

Zhang(Yi),Zhou(Lin),Unadkat(Jashvant D),Ma... J Pharm Sci 2010-01-14

...Bcrp1(-/-) mice was decreased by approximately 70% by pregnancy. In conclusion, since Bcrp1 plays a minor role in the sy...

上一页 4 5 6 7 8 9 10 11 12 下一页 8 / 共 20

联系地址

山东省济南市章丘区文博路2号

齐鲁师范学院 genelibs生信实验室

山东省济南市高新区舜华路750号

大学科技园北区F座4单元2楼

电话: 0531-88819269

微信公众号

关注微信订阅号,实时查看信息,关注医学生物学动态。


商务邮箱

E-mail: [email protected]