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4-MEC potentially triggers CAV1 via the BDNF-TrkB signaling pathway.

Zhang(W),Cao(F),Li(M),Fan(Z),Wu(L),Liu(W),... Mol Cell Neurosci 2026-03-00

...CAV1 knockdown abolished 4-MEC-induced increases in these proteins and neuroplasticity-related mRNAs, whereas CAV1 overe...

Role of Caveolae and Caveolin in Vascular Physiology and Pathology.

Zhang(C),Hu(W),Zhang(J),Wang(Z),Lu(H) J Am Heart Assoc 2026-02-17

...CAV1, CAV2, CAV3) and regulated by Cavins-orchestrate membrane dynamics, mechanotransduction, and lipid trafficking in e...

Canagliflozin Reduces Proteinuria and Mitochondrial Fission in Membranous Nep...

Lv(X),Cui(L),Liu(H),Wei(H),Xu(J),He(D),Yan... Am J Nephrol 2026-02-20

...CAV1) is upregulated in MN, and we hypothesized canagliflozin alleviates MN via inhibiting the CAV1/PKA/DRP1 pathway. Th...

Activated protein C drives β-arrestin-2- and c-Src-dependent phosphorylation ...

Qin(H),Orduña-Castillo(LB),Molinar-Inglis(... J Biol Chem 2026-03-00

...Cav1 in intact cells through an N-terminal aromatic-rich Cav1 binding motif. Mutation of this motif disrupts GRK5-Cav1 b...

Caveola and Its Resident Proteins, Caveolin-1 and -2, Play Critical Roles in ...

Yu(RMC),Oguz(G),Fu(NY),Shihabuddeen(WA),Ch... Invest Ophthalmol Vis Sci 2026-08-03

...CAV1/2 overexpression also significantly inhibited tube formation, whereas knockdown of CAV1 or CAV2 enhanced tube forma...

Caveolin-1 deficiency exacerbates liver fibrosis by driving lipid metabolic r...

Wang(Y),Wang(X),Lin(J),Zhang(W),Sun(Y),Gen... Free Radic Biol Med 2026-07-00

...CAV1) as a critical suppressor of HSC activation. CAV1 deficiency enhances DRP1-mediated mitochondrial fission, elevatin...

Membrane Curvature Generation by the Caveolin 8S Complex and the Role of Chol...

Vasquez Rodriguez(SY),Lazaridis(T) J Chem Theory Comput 2026-09-08

The protein caveolin-1 (Cav1) is essential in the generation of caveolae, but the mechanism of its action remains unclea...

Palmitoyltransferase DHHC7 mediates protein palmitoylation and is essential f...

Zheng(H),Cheng(X),Hao(W),Sun(P),Xue(Y),Ye(... Front Cell Dev Biol None

...CAV1). To explore DHHC7's role in sperm function, sperm were treated with a specific DHHC7 antibody. Subsequently, sperm...

Goatpox virus Hrf-063 interacts with host eIF4A1 and is associated with alter...

Long(B),Wang(H),Yu(L),Liu(B),Xu(M),Amantai... Front Cell Infect Microbiol None

...CAV1, and Hrf-063 regulated ISG15 and STING1 transcription in a time- and infection-dependent manner. TCID50 assays furt...

Trabecular-Like Scaffold Dictates Osteogenesis via Fluid Shear Stress-Induced...

Gong(W),Zhang(J),Liu(X),Zhou(S),Huang(K),J... Research (Wash D C) None

...CAV1) as a prominent FSS-responsive membrane regulator. Mechanistically, CAV1 enhanced phosphatidylinositol 3-kinase (PI...

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