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APC(cdh1) mediates degradation of the oncogenic Rho-GEF Ect2 after mitosis.

Liot(Caroline),Seguin(Laetitia),Siret(Auré... PLoS One 2012-02-24

...CUX1 regulate expression of MgcRacGAP and Ect2 as cells enter S-phase.,We now report that Ect2 is subject to proteasomal...

Transcription of the human EAP1 gene is regulated by upstream components of a...

Mueller(Johanna K),Koch(Ines),Lomniczi(Ale... Mol Cell Endocrinol 2012-10-09

...CUX1 in this context is not known, but like EAP1, CUX1 can either activate or repress gene transcription. We observed th...

Ectopic expression of Cux1 is associated with reduced p27 expression and incr...

Paul(Binu M),Vassmer(Dianne),Taylor(Aaron)... Dev Dyn 2011-10-03

...Cux1 was ectopically expressed in the cyst lining epithelial cells of newborn, P7 and P15 Pkd1(CD) mice. Cux1 expression...

Dpy19l1, a multi-transmembrane protein, regulates the radial migration of glu...

Watanabe(Keisuke),Takebayashi(Hirohide),Be... Development 2011-12-20

...Cux1, which is a marker for upper layer neurons, suggesting that Dpy19l1 knockdown results in migration defects but does...

MicroRNA122 is a key regulator of α-fetoprotein expression and influences the...

Kojima(Kentaro),Takata(Akemi),Vadnais(Char... Nat Commun 2011-10-18

...CUX1/microRNA214/ZBTB20 pathway regulates AFP expression. We also show that the microRNA122/CUX1/RhoA pathway regulates ...

High doses of TGF-β potently suppress type I collagen via the transcription f...

Fragiadaki(Maria),Ikeda(Tetsurou),Witherde... Mol Biol Cell 2011-09-26

...CUX1 acts as a negative regulator of TGF-β and potent inhibitor of type I collagen transcription. We show that CUX1, a C...

The roles of CUX1 homeodomain proteins in the establishment of a transcriptio...

Kedinger(Valérie),Nepveu(Alain) Cell Adh Migr 2011-01-20

...CUX1, while some genes that inhibit cell motility are repressed by CUX1. The dual function of CUX1 as an activator and r...

Cux1 transcription factor is induced in inflammatory bowel disease and protec...

Darsigny(Mathieu),St-Jean(Stéphanie),Boudr... Inflamm Bowel Dis 2011-01-28

...CUX1 expression in IBD patients. The Cux1(ΔHD/ΔHD) hypomorphic mouse model (Cux1ΔHD) treated with DSS in drinking water ...

Exogenous nucleosides modulate expression and activity of transcription facto...

Ortega(Ángeles),Gil(Ángel),Sánchez-Pozo(An... J Nutr Biochem 2011-10-21

...CUX1), v-ets avian erythroblastosis virus E26 oncogene homolog 1 (ETS1) and SMAD family member 2. In contrast, NS additi...

Asynchronous expression of the homeodomain protein CUX1 in Sertoli cells and ...

Kroll(Melissa R),Viss(Engela S),Lamb(Jonat... Biol Reprod 2011-06-14

...CUX1 protein develop renal hyperplasia associated with reduced expression of the cyclin kinase inhibitor p27. A 55-kDa C...

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