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Mutant KRAS associated malic enzyme 1 expression is a predictive marker for rad…

Chakrabarti(Gaurab) Radiat Oncol 2016-03-25

...GOT1 expression had significantly worse outcomes after radiotherapy, but this was not seen after chemotherapy alone.,KRA...

Identification of Regulatory and Cargo Proteins of Endosomal and Secretory Path…

Heard(William),Sklenář(Jan),Tomé(Daniel F A)… Mol Cell Proteomics 2016-04-05

...GOT1), which localizes to the Golgi, clathrin light chain 2 (CLC2) labeling clathrin-coated vesicles and pits and the ve...

Altered hepatic sulfur metabolism in cystathionine β-synthase-deficient homocys…

Jiang(Hua),Stabler(Sally P),Allen(Robert H),… FASEB J 2015-08-25

...GOT1) and mitochondrial (GOT2) isoforms of glutamic-oxaloacetic transaminase were repressed in HCU animals by 86 and 30%...

GOT1/AST1 expression status as a prognostic biomarker in pancreatic ductal aden…

Feld(Fenja M),Nagel(Philipp D),Weissinger(St… Oncotarget 2015-12-14

...GOT1 link has not been determined in primary human patient samples. Here we studied the GOT1 expression status as a prog...

Targeting glutamine metabolism sensitizes pancreatic cancer to PARP-driven meta…

Chakrabarti(Gaurab),Moore(Zachary R),Luo(Xiu… Cancer Metab 2015-10-14

...GOT1 (cytoplasmic glutamate oxaloacetate transaminase 1), and GOT2 (mitochondrial glutamate oxaloacetate transaminase 2)...

An Essential Role of the Mitochondrial Electron Transport Chain in Cell Prolife…

Birsoy(Kıvanç),Wang(Tim),Chen(Walter W),Frei… Cell 2015-10-28

...GOT1, the cytosolic aspartate aminotransferase, loss of which kills cells upon ETC inhibition. GOT1 normally consumes as...

Metabolic phenotypes in pancreatic cancer.

Yu(Min),Zhou(Quanbo),Zhou(Yu),Fu(Zhiqiang),T… PLoS One 2015-11-23

...GOT1. Based on the expression of metabolism-related proteins, the metabolic phenotypes of tumors were classified into tw...

Aspirin inhibits cell viability and mTOR downstream signaling in gastroenteropa…

Spampatti(Matilde),Vlotides(George),Spöttl(G… World J Gastroenterol 2015-05-18

...GOT1 neuroendocrine tumor cells were treated with different concentrations of aspirin (from 0.001 to 5 mmol/L), and the ...

Whole genome transcript profiling of drug induced steatosis in rats reveals a g…

Sahini(Nishika),Selvaraj(Saravanakumar),Borl… PLoS One 2015-07-24

...GOT1, LDLR, GK, STAT3, and PKLR) as signature genes to predict DIS. Moreover, cross tabulation revealed 9 genes to be re...

Anticancer effects of metformin on neuroendocrine tumor cells in vitro.

Vlotides(George),Tanyeri(Ayse),Spampatti(Mat… Hormones (Athens) 2015-10-01

...GOT1 neuroendocrine tumor cells with increasing concentrations of metformin (0.1-10 mM) dose-dependently suppressed cell...

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