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The anti-inflammatory effect of 2-(4-hydroxy-3-prop-2-enyl-phenyl)-4-prop-2-eny…

Liao(Hsiang-Ruei),Chien(Ching-Ru),Chen(Jih-J… Chem Biol Interact 2015-08-25

...Hck, Fgr kinase activity (other members of Src kinase), downstream phosphorylation of Vav1 and extracellular signal-regu...

The Src-Family Kinases Hck and Fgr Regulate Early Lipopolysaccharide-Induced My…

Mazzi(Paola),Caveggion(Elena),Lapinet-Vera(J… J Immunol 2015-12-15

...Hck- and Fgr-deficient mice show a profound impairment in early recruitment of neutrophils and monocytes in response to ...

HIV-1 reprograms the migration of macrophages.

Vérollet(Christel),Souriant(Shanti),Bonnaud(… Blood 2015-04-27

...Hck and Wiskott-Aldrich syndrome protein (WASP), 2 major regulators of podosomes. In conclusion, HIV-1 reprograms macrop...

A positive feedback loop between Gli1 and tyrosine kinase Hck amplifies shh sig…

Shi(X),Zhan(X),Wu(J) Oncogenesis 2015-12-01

...Hck as a novel activator of Gli1. In Shh-responsive NIH3T3 cells, Hck interacts with Gli1 and phosphorylates multiple ty...

HIV-1 Infection of T Lymphocytes and Macrophages Affects Their Migration via Ne…

Vérollet(Christel),Le Cabec(Véronique),Marid… Front Immunol 2015-10-27

...Hck, which in turn phosphorylates the Wiskott-Aldrich syndrome protein (WASP). WASP is a key player in actin remodeling ...

Differential sensitivity of Src-family kinases to activation by SH3 domain disp…

Moroco(Jamie A),Craigo(Jodi K),Iacob(Roxana … PLoS One 2015-11-10

...Hck, Lyn and Fyn to SH3-based activation in a kinetic kinase assay. All four SFKs responded to VSL12 binding with enhanc...

Interaction with the Src homology (SH3-SH2) region of the Src-family kinase Hck…

Alvarado(John Jeff),Tarafdar(Sreya),Yeh(Joan… J Biol Chem 2015-02-06

...Hck SH3 Glu-93 interfered with Nef·Hck complex formation and kinase activation in cells. The Hck SH2 domains impinge on ...

Mechanisms of interferon-γ production by neutrophils and its function during St…

Gomez(John C),Yamada(Mitsuhiro),Martin(Jessi… Am J Respir Cell Mol Biol 2015-04-21

...Hck/Lyn/Fgr Src family tyrosine kinases, and NADPH oxidase. Our current studies examined the mechanisms that regulate IF...

Human umbilical cord mesenchymal stem cells and derived hepatocyte-like cells e…

Zhou(Ruiping),Li(Zhuokun),He(Chengyi),Li(Ron… PLoS One 2015-11-30

...hCK-18), α-fetoprotein (hAFP), albumin (hALB), and hepatocyte-specific functions glycogen storage and urea metabolism. W...

An efficient siRNA-mediated gene silencing in primary human monocytes, dendriti…

Troegeler(Anthony),Lastrucci(Claire),Duval(C… Immunol Cell Biol 2015-05-25

...Hck) shows for the first time that this kinase regulates the protease-dependent migration mode in human monocytes. Colle...

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