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Protein phosphatase 4 catalytic subunit regulates Cdk1 activity and microtubu...

Toyo-oka(Kazuhito),Mori(Daisuke),Yano(Yosh... J Cell Biol 2008-04-29

...NDEL1 is a substrate of PP4c, and PP4c selectively dephosphorylates NDEL1 at Cdk1 sites. We also demonstrate that PP4c n...

What can we learn from the disrupted in schizophrenia 1 interactome: lessons ...

Camargo(Luiz M),Wang(Qi),Brandon(Nicholas ... Novartis Found Symp 2008-08-07

...Ndel1-EOPA with Hayashi and colleagues. Many components of the interactome are themselves now being shown to be schizoph...

Ndel1 controls the dynein-mediated transport of vimentin during neurite outgr...

Shim(Su Yeon),Samuels(Benjamin Adam),Wang(... J Biol Chem 2008-06-19

...Ndel1 promotes neurite outgrowth, neuronal migration, and cell integrity (1-6). To further understand the roles of Ndel1...

The structure of the coiled-coil domain of Ndel1 and the basis of its interac...

Derewenda(Urszula),Tarricone(Cataldo),Choi... Structure 2008-03-11

Ndel1 and Nde1 are homologous and evolutionarily conserved proteins, with critical roles in cell division, neuronal migr...

Elucidating the relationship between DISC1, NDEL1 and NDE1 and the risk for s...

Burdick(Katherine E),Kamiya(Atsushi),Hodgk... Hum Mol Genet 2008-09-15

...NDEL1-DISC1 protein interaction, there have been no investigations of the NDEL1 gene or the relationship between NDEL1 a...

Insolubility of disrupted-in-schizophrenia 1 disrupts oligomer-dependent inte...

Leliveld(S Rutger),Bader(Verian),Hendriks(... J Neurosci 2008-05-08

...NDEL1. Recombinant (r) NDEL1 expressed in Escherichia coli selectively bound an octamer of an rDISC1 fragment but not di...

Neuroepithelial stem cell proliferation requires LIS1 for precise spindle ori...

Yingling(Jessica),Youn(Yong Ha),Darling(Da... Cell 2008-03-06

...NDEL1 restores cortical microtubule and dynein localization in Lis1-deficient cells. Thus, control of symmetric division...

Ndel1 promotes axon regeneration via intermediate filaments.

Toth(Cory),Shim(Su Yeon),Wang(Jian),Jiang(... PLoS One 2008-05-28

...Ndel1, emergently viewed as an integrator of the cytoskeleton, in axon regeneration. Ndel1 was synthesized de novo and u...

Lis1 and Ndel1 influence the timing of nuclear envelope breakdown in neural s...

Hebbar(Sachin),Mesngon(Mariano T),Guillott... J Cell Biol 2008-10-13

Lis1 and Ndel1 are essential for animal development. They interact directly with one another and with cytoplasmic dynein...

LIS1 and NDEL1 coordinate the plus-end-directed transport of cytoplasmic dynein.

Yamada(Masami),Toba(Shiori),Yoshida(Yuko),... EMBO J 2008-10-27

...NDEL1 releases the blocking effect of LIS1 on cytoplasmic dynein. We demonstrate that LIS1, cytoplasmic dynein and MT fr...

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