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Pregnancy associated plasma protein-A links pregnancy and melanoma progression …

Prithviraj(Prashanth),Anaka(Matthew),McKeown… Oncotarget 2016-05-12

...PAPPA), a pregnancy-associated metalloproteinase produced by the placenta that increases the bioavailability of IGF1 by ...

Female PAPP-A knockout mice are resistant to metabolic dysfunction induced by h…

Hill(Cristal M),Arum(Oge),Boparai(Ravneet K)… Age (Dordr) 2016-01-13

...PAPPA). In vitro, PAPP-A is regulated by pro-inflammatory cytokines (PICs) such as interleukin (IL)-6 and tumor necrosis...

Causal Modeling of Cancer-Stromal Communication Identifies PAPPA as a Novel Str…

Engelmann(Julia C),Amann(Thomas),Ott-Rötzer(… PLoS Comput Biol 2016-02-22

...PAPPA) was among the latter. Further support for the predicted effect of PAPPA on HCC cells came from both in vitro stud...

First-Trimester Serum Acylcarnitine Levels to Predict Preeclampsia: A Metabolom…

Koster(Maria P H),Vreeken(Rob J),Harms(Amy C… Dis Markers 2016-02-29

...PAPPA, PLGF, taurine, and stearoylcarnitine (AUC = 0.784). The best prediction model for LO-PE consisted of MC, MAP, PAP...

Placental DNA methylation at term reflects maternal serum levels of INHA and FN…

Wilson(Samantha L),Blair(John D),Hogg(Kirste… BMC Med Genet 2016-04-12

...PAPPA, though not significant. INHBA and FN1 DNAm was associated with gestational-age corrected birth weight, while INHA...

MicroRNA-141 inhibits vascular smooth muscle cell proliferation through targeti…

Zhang(Yudong),Chen(Bainan),Ming(Liu),Qin(Hon… Int J Clin Exp Pathol 2016-10-28

...PAPPA was the direct target gene of miR-141. Overexpression of PAPPA impaired the miR-141-induced inhibition of prolifer...

Copy number variants in patients with short stature.

van Duyvenvoorde(Hermine A),Lui(Julian C),Ka… Eur J Hum Genet 2015-01-26

...PAPPA). Besides six CNVs known to be causative for short stature, 40 CNVs with possible pathogenicity were identified. S...

Whole-genome reconstruction and mutational signatures in gastric cancer.

Nagarajan(Niranjan),Bertrand(Denis),Hillmer(… Genome Biol 2015-12-17

...PAPPA as a recurrently mutated gene in TP53 wild-type gastric cancer.,These results highlight how whole-genome cancer se...

[Esthetic and functional improvement in proximal femoral focal deficiency with …

Feusi(A D),Tschanz(H),Exner(G U) Orthopade 2015-07-01

...Pappas) have no femoral or only abortive femoral head development. Winkelmann published a case of one patient treated wi...

Eliminating first trimester markers: will replacing PAPP-A and βhCG miss women …

Dukhovny(Stephanie),Zera(Chloe),Little(Sarah… J Matern Fetal Neonatal Med 2015-08-03

...PAPPA-A and βhCG from 658 euploid singleton pregnancies from a prospective longitudinal cohort. Analytes were standardiz...

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