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Frequency of copy number abnormalities in common genes associated with B-cell p…

Barbosa(Thayana Conceição),Terra-Granado(Eug… Cancer Genet 2016-01-05

...PBX1 was frequently deleted in RB1, and an absence of deletions was observed in IKZF1 and genes localized to the PAR1 re...

The pioneer factor PBX1 is a novel driver of metastatic progression in ERα-posi…

Magnani(Luca),Patten(Darren K),Nguyen(Van T … Oncotarget 2016-08-03

...PBX1 translates epigenetic cues and mediates estrogen induced ERα binding. Here we demonstrate that PBX1 plays a central...

Genomics and drug profiling of fatal TCF3-HLF-positive acute lymphoblastic leuk…

Fischer(Ute),Forster(Michael),Rinaldi(Anna),… Nat Genet 2016-01-13

...PBX1-positive ALL. We identified recurrent intragenic deletions of PAX5 or VPREB1 in constellation with the fusion of TC...

Thoracic Myoepithelial Tumors: A Pathologic and Molecular Study of 8 Cases With…

Leduc(Charles),Zhang(Lei),Öz(Buge),Luo(Jean)… Am J Surg Pathol 2016-05-17

...PBX1, EWSR1-ZNF444, and FUS-KLF17 fusions identified in 1 case each and 1 case having EWSR1 rearrangement with no partne...

Meis2 is essential for cranial and cardiac neural crest development.

Machon(Ondrej),Masek(Jan),Machonova(Olga),Kr… BMC Dev Biol 2016-08-29

...Pbx1, 2 and 3 and Meis1 documented specific functions in embryogenesis, however, functional studies of Meis2 in mouse ar...

[Molecular analysis of childhood B-acute lymphoblastic leukemia: Identification…

Kumar(D),Panigrahi(M K),Saikia(K K),Kapoor(G… Mol Biol (Mosk) 2016-02-23

...PBX1, MLL-AF4) in childhood B-ALL. In this study we show the prevalence of these common gene rearrangements and also exp...

Pbx Regulates Patterning of the Cerebral Cortex in Progenitors and Postmitotic …

Golonzhka(Olga),Nord(Alex),Tang(Paul L F),Li… Neuron 2016-04-28

We demonstrate using conditional mutagenesis that Pbx1, with and without Pbx2(+/-) sensitization, regulates regional ide...

[Clinical significance of monitoring E2A- PBX1 fusion gene expression in patien…

Zhao(Xiaosu),Qin(Yazhen),Zhang(Yanling),Xu(Y… Zhonghua Xue Ye Xue Za Zhi 2016-06-10

...PBX1 by RQ-PCR could be used to evaluate MRD status after allo-HSCT. Patients with positive E2A-PBX1 at early stage of t...

The Histone Variant MacroH2A1.2 Is Necessary for the Activation of Muscle Enhan…

Dell'Orso(Stefania),Wang(A Hongjun),Shih(Han… Cell Rep 2016-11-01

...Pbx1 at prospective enhancers are regulated by mH2A1.2. Overall, our findings indicate a role of mH2A1.2 in marking regu...

ChIP-BIT: Bayesian inference of target genes using a novel joint probabilistic …

Chen(Xi),Jung(Jin-Gyoung),Shajahan-Haq(Ayesh… Nucleic Acids Res 2016-09-21

...PBX1 ChIP-seq data acquired from MCF-7 breast cancer cells. TF knockdown experiments have initially validated about 30% ...

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