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Di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT) overcomes multidru…

Jansson(Patric J),Yamagishi(Tetsuo),Arvind(A… J Biol Chem 2015-06-26

...Pgp substrate. Indeed, Pgp-dependent lysosomal damage and cytotoxicity of Dp44mT were abrogated by Pgp inhibitors, Pgp s...

Influence of different chemicals on MDR-1 P-glycoprotein expression and activit…

Romiti(Nadia),Tramonti(Gianfranco),Chieli(El… Toxicol Appl Pharmacol 2002-11-05

...Pgp mRNA expression was studied by RT-PCR and the amount of Pgp was determined by Western blotting. Pgp activity was ass...

Collagen-Derived N-Acetylated Proline-Glycine-Proline in Intervertebral Discs M…

Feng(Chencheng),Zhang(Yang),Yang(Minghui),Hu… Stem Cells 2016-10-27

...PGP receptors (CXCR1 and CXCR2) in CESCs was upregulated by N-Ac-PGP. Additionally, N-Ac-PGP induced F-actin cytoskeleta...

Tumor stressors induce two mechanisms of intracellular P-glycoprotein-mediated …

Al-Akra(L),Bae(DH),Sahni(S),Huang(MLH),Park(… J Biol Chem 2018-00-09

...Pgp redistribution to lysosomes; 2) increased Pgp expression; 3) lysosomal biogenesis; and 4) potentiation of Pgp substr...

Distinction of virgin and memory T lymphocytes. Stable acquisition of the Pgp-1…

Budd(R C),Cerottini(J C),Horvath(C),Bron(C),… J Immunol 1987-06-10

...Pgp-1. The appearance of peripheral Pgp-1- T cells was found to be thymus dependent, as demonstrated by the diminished p...

Prevention and follow-up of cardiovascular disease among patients without a per…

Devroey(D),Coigniez(P),Vandevoorde(J),Kartou… Fam Pract 2003-12-04

...PGP. The mean age of patients without a PGP (33.2 +/- 20.4 years) is significantly lower than for those with a PGP (40.4...

Human intestinal P-glycoprotein activity estimated by the model substrate digox…

Larsen(U L),Hyldahl Olesen(L),Guldborg Nyvo… Scand J Clin Lab Invest 2007-05-08

...Pgp activity (p<0.05), whereas SNP 2677 apparently did not affect Pgp activity. No variation in Pgp in relation to age o...

Analysis of the interaction of induction regimens with p-glycoprotein expressio…

Pallis(M),Hills(R),White(P),Grundy(M),Russel… Blood Cancer J 2012-10-02

...Pgp-positive and Pgp-negative patients. In patients treated with DA/ADE, 78% of Pgp-positive and 90% of Pgp-negative cas...

Analysis of random recombination between human MDR1 and mouse mdr1a cDNA in a p…

Shoshani(T),Zhang(S),Dey(S),Pastan(I),Gottes… Mol Pharmacol 1998-10-30

...Pgp cells stained less well with human-specific anti-Pgp mAb MRK16 than wild-type Pgp, despite having the described epit...

Interindividual variation in expression of P-glycoprotein in normal human liver…

Schuetz(E G),Furuya(K N),Schuetz(J D) J Pharmacol Exp Ther 1995-12-19

...Pgp and in the mRNA for Pgp (MDR1) in liver from 41 individuals. These samples were divided into two groups, normal and ...

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