Theodorou(Vassiliki),Kimm(Melanie A),Boer(... Nat Genet 2007-08-14

...Rspo3, as an oncogene by overexpression in a p53-deficient mammary epithelial cell line. The human orthologs of the cand...

Aoki(Motoko),Mieda(Michihiro),Ikeda(Toshio... Dev Biol 2007-03-05

Mouse R-spondin3 (Rspo3) is a member of the R-spondin protein family, which is characterized by furin-like cysteine-rich...

Gattelli(Albana),Zimberlin(María N),Meiss(... J Virol 2006-12-04

...Rspo3, which is overexpressed in three of the eight independent tumor lines and codes for a protein very similar to the ...

Madan(B),Ke(Z),Harmston(N),Ho(S Y),Frois(A... Oncogene 0000-00-00

...RSPO3-translocated cancers causes a marked remodeling of the transcriptome, with loss of cell cycle, stem cell and proli...

Rocha(Ana Sofia),Vidal(Valerie),Mertz(Marj... Cell Rep 0000-00-00

...Rspo3 in mice disrupts activation of central fate, demonstrating its crucial role in determining and maintaining β-caten...

Recouvreux(María Sol),Grasso(Esteban Nicol... Oncotarget 0000-00-00

...RSPO3) and Gap Junction protein Alpha 1 (GJA1) promoters. This binding upregulates Rspo3 oncogene expression and downreg...

Sekine(Shigeki),Yamashita(Satoshi),Tanabe(... J Pathol 0000-00-00

...RSPO3 fusions (31%) and RNF43 mutations (24%) were frequently and almost exclusively observed in TSAs. Consistent with t...

Vidal(Valerie),Sacco(Sonia),Rocha(Ana Sofi... Genes Dev 0000-00-00

...RSPO3 leads to loss of SHH signaling and impaired organ growth. Importantly, Rspo3 function remains essential in adult l...

Chang(Chiung-Fang),Hsu(Li-Sung),Weng(Chieh... Int J Mol Sci 0000-00-00

...Rspo3 are both N-glycosylated at N137, a site near the C-terminus of the furin repeat 2 domain, and Rspo2 is N-glycosyla...

Hilkens(John),Timmer(Nikki C),Boer(Mandy),... Gut 0000-00-00

...RSPO3 in parallel.,We generated a conditional Rspo3 transgenic mouse model in which the Rspo3 transgene is expressed upo...