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The role of TEAD4 in trophectoderm commitment and development is not conserved …

Pérez-Gómez(A),González-Brusi(L),Flores-Boro… Development 2024-10-15

...TEAD4 was required for post-hatching development. TEAD4 KO spherical conceptuses showed normal development of the embryo...

Radiation-induced YAP/TEAD4 binding confers non-small cell lung cancer radiores…

Wang(M),Yi(J),Gao(H),Wei(X),Xu(W),Zhao(M),Zh… Cell Death Dis 2024-08-26

...TEAD4. Notably, when inhibiting YAP binds to TEAD4, it inhibits NRP1 expression, and Rescue experiments show that YAP/TE...

G-quadruplexes formation within the promoter of TEAD4 oncogene and their intera…

Cozzaglio(M),Ceschi(S),Groaz(E),Sturlese(M),… Front Chem 2022-00-00

...TEAD4 oncogene. TEAD4 codifies for a transcriptional enhancer factor, TEAD4, that actively promotes EMT, supporting, cel...

Tetrastigma Hemsleyanum Polysaccharide Suppresses Triple-Negative Breast Cancer…

Shang(Y),Si(W),Zhang(Y),Liu(J),Zhang(H),Li(Y… Adv Sci (Weinh) 2026-06-00

...TEAD4 interaction and abolishes TEAD4 DNA-binding activity. Moreover, THP downregulates TEAD4 expression. These combined...

TEAD4 is a novel independent predictor of prognosis in LGG patients with IDH mu…

Yuan(HY),Lv(YJ),Chen(Y),Li(D),Li(X),Qu(J),Ya… Open Life Sci 2021-00-00

...TEAD4 CNV increase showed higher expression level of TEAD4 gene. In LGG patients with IDH mutation, those with higher TE...

Upregulation of CDC25B by transcription factor TEAD4 drives invasion and inhibi…

Zhang(T),Chen(L),Li(S),Shen(C) Anticancer Drugs 2024-00-01

...TEAD4 expression levels in stomach adenocarcinoma tissues and enriched pathways of CDC25B were analyzed. qRT-PCR of CDC2...

Molecular dynamics simulations study of influence of Tyr422Ala mutation on tran…

Niu(RJ),Zheng(QC),Zhang(HX) J Theor Biol 2019-00-07

...TEAD4-TAZ complex (PDB Code 5GN0) in mouse reveals that the interactions between the two helices of YAP/TAZ and TEAD4 ar...

Integrative genomics analysis reveals the multilevel dysregulation and oncogeni…

Lim(B),Park(JL),Kim(HJ),Park(YK),Kim(JH),Soh… Carcinogenesis 2014-05-00

...TEAD4) and Yes-associated protein 1 (YAP1)] and targets (CRIM1, CYR61, CTGF and ITGB2), are concurrently hypomethylated ...

Transcription factor TEAD4 regulates expression of myogenin and the unfolded pr…

Benhaddou(A),Keime(C),Ye(T),Morlon(A),Michel… Cell Death Differ 2012-02-00

...TEAD4 results in abnormal differentiation characterised by the formation of shortened myotubes. Chromatin immunoprecipit...

Deciphering a distinct regulatory network of TEAD4, CDX2 and GATA3 in humans fo…

Xiao(L),Ma(L),Wang(Z),Yu(Y),Lye(SJ),Shan(Y),… Biochim Biophys Acta Mol Cell… 2020-00-00

...TEAD4, CDX2 or GATA3 to study their roles during this process. Although hESCs with TEAD4 deletion maintain pluripotency,...

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