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Transforming growth factor-beta isoforms differently stimulate proalpha2 (I) ...

Kinbara(Takuro),Shirasaki(Fumiaki),Kawara(... J Cell Physiol 2002-03-06

...COL1A2) during the wound healing process. For this purpose, we utilized transgenic mice harboring the -17 kb promoter se...

Halofuginone inhibition of COL1A2 promoter activity via a c-Jun-dependent mec...

McGaha(Tracy L),Kodera(Takao),Spiera(Harry... Arthritis Rheum 2002-11-14

...COL1A2 promoter, whereas the expression of a dominant-negative c-Jun construct abolished this effect. Northern blotting ...

Ets1 is an effector of the transforming growth factor beta (TGF-beta ) signal...

Czuwara-Ladykowska(Joanna),Sementchenko(Vi... J Biol Chem 2002-07-12

...COL1A2 promoter demonstrated that Ets1 in the presence of TGF-beta signaling interferes with the stimulatory role of p30...

Role of p38 MAPK in transforming growth factor beta stimulation of collagen p...

Sato(Madoka),Shegogue(Daniel),Gore(Elizabe... J Invest Dermatol 2002-05-08

...COL1A2 promoter activity and potentiated transforming growth factor beta stimulation of this promoter. The p38 response ...

Deletions and duplications of Gly-Xaa-Yaa triplet repeats in the triple helic...

Pace(J M),Atkinson(M),Willing(M C),Wallis(... Hum Mutat 2002-01-22

...COL1A2 collagen genes. Triple helix formation was impaired, type I collagen alpha chains were post-translationally overm...

Adenovirus-mediated overexpression and stimulation of the human angiotensin I...

Warnecke(C),Kaup(D),Marienfeld(U),Poller(W... J Mol Med (Berl) 2002-01-14

...COL1A2/GAPDH (a) and COL1A2/beta-actin (b) ratios revealed no differences between AT2R-transduced fibroblasts and antise...

Sp1 and Smad proteins cooperate to mediate transforming growth factor-beta 1-...

Poncelet(A C),Schnaper(H W) J Biol Chem 2001-07-19

...COL1A2) activation in human glomerular mesangial cells, potentially contributing to glomerulosclerosis. Here, we report ...

Synergistic cooperation between Sp1 and Smad3/Smad4 mediates transforming gro...

Zhang(W),Ou(J),Inagaki(Y),Greenwel(P),Rami... J Biol Chem 2001-02-08

...COL1A2 up-regulation. Recombinant Smad3 and Smad4 bind in vitro to the CAGA box of COL1A2; TGFbeta treatment of cultured...

Antagonistic regulation of type I collagen gene expression by interferon-gamm...

Ghosh(A K),Yuan(W),Mori(Y),Chen Sj,Varga(J... J Biol Chem 2001-05-24

...COL1A2) promoter activity through the cellular Smad signal transduction pathway. In contrast, IFN-gamma activates Stat1a...

Sequence of normal canine COL1A1 cDNA and identification of a heterozygous al...

Campbell(B G),Wootton(J A),MacLeod(J N),Mi... Arch Biochem Biophys 2001-01-25

...COL1A2 cDNA were each amplified by RT-PCR using primers containing 5' T7 polymerase sites. These PCR products were trans...

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