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Evaluation of TAM Receptor Targeting in Pathophysiology of Idiopathic Pulmonary…

Vercellino(N),Ferreira(LL),Zoppis(E),Di Tizi… Medicina (Kaunas) 2025-10-14

...COL1A1, and FN1 in HPFs and IPF FBs compared to TGF-β treatment. HPFs and IPF FBs co-cultured with monocyte-derived macr...

Transcriptomic Signatures in IgA Nephropathy: From Renal Tissue to Precision Ri…

Delrue(C),Speeckaert(MM) Int J Mol Sci 2025-10-15

...COL1A1) and altered pathways (e.g., NF-κB, TGF-β, JAK/STAT, and complement) that are associated with clinical decline. S...

Empagliflozin Attenuates Liver Inflammation and Fibrosis in NAFLD: Evidence fro…

Fu(C),Deng(L),Zhu(X),Wang(B),Hu(B),Xue(H),Ze… Curr Issues Mol Biol 2025-10-15

...COL1A1, while modulating TIMP-1 and MMP-9 expression. Collectively, these findings reveal that empagliflozin ameliorates...

Engineering an Injectable Scaffold with Enhanced ECM Mimicry for Cell Delivery …

Kirwale(SS),Jaiswal(R),Sahu(P),Verma(V),Yada… ACS Biomater Sci Eng 2025-10-13

...Col1A1, and TGF-β. In vivo application of PDF-loaded CHyCoGel significantly enhanced wound healing, epithelialization, a...

A multi-omics pipeline integrating machine learning and spatial-cellular analys…

Dai(Z),Shan(X),Kang(Y),Chen(Y),Feng(Q),Cai(Z… Int J Surg 2025-12-01

...COL1A1, EMP1, MYH11, SASH1) were robustly selected by all four machine learning algorithms. Multi-omics validation revea...

Single-cell RNA sequencing reveals oocyte-granulosa crosstalk and regulatory ne…

Zhang(X),Li(D),He(H),Ma(Q),Lu(Y),Yu(M) Int J Biol Macromol 2025-12-00

...COL1A1, COL3A1), proliferation regulation (PCNA, MCM3), and cellular communication (NTN1). CellChat analysis enhanced cr...

Orally Administered Edible Snail Extract Powder Enhances Skin Hydration via Hya…

Lee(C),Baek(S),Lim(W),Lim(TG) Food Sci Nutr 2025-10-00

...Col1a1, Col3a1, Tgf-β1, Flg, and Cers2, along with downregulation of Hyal1 and Acer1. These effects were supported by hi...

Design and synthesis of genipine derivatives for the treatment of liver fibrosi…

Cao(Y),Yu(J),Zhu(Y),Wu(E),Hu(Z),Miao(H),Ren(… Eur J Med Chem 2025-10-15

...COL1A1) induced by TGF-β1, and has excellent in vitro safety. In a mouse model of CCl4-induced hepatic fibrosis, C9 exhi...

Integrative multi-omics and causal inference reveal periodontal ligament cell-m…

Jiang(Y),Zhou(J),Huang(Y),Bai(Y),Chen(X),Hua… Prog Orthod 2025-10-20

...COL1A1/COL2A1 downregulation. Single-cell RNA sequencing identified Cd40+ macrophages enriched in IL-17 signaling. MR ca...

Senolytic Combination of Dasatinib and Quercetin Promotes Tendon-to-Bone Healin…

Cai(Z),Wang(H),Hu(J),Qu(C),Chen(S),Liu(X),Fa… Am J Sports Med 2025-11-00

...Col1a1, Tnmd, and Scx) genes. Histological analysis revealed that the aged + DQ group had decreased cellular senescence ...

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