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Fli-1 inhibits collagen type I production in dermal fibroblasts via an Sp1-de...

Czuwara-Ladykowska(J),Shirasaki(F),Jackers... J Biol Chem 2001-07-19

...COL1A2) mRNA was inhibited following stable transfection of Fli-1 in dermal fibroblasts. Subsequent analysis of the COL1...

Identification of novel TGF-beta /Smad gene targets in dermal fibroblasts usi...

Verrecchia(F),Chu(M L),Mauviel(A) J Biol Chem 2001-07-05

...COL1A2, COL3A1, COL6A1, COL6A3, and tissue inhibitor of metalloproteases-1 as definite TGF-beta/Smad3 targets. Extrapola...

Characterization of an evolutionarily conserved far-upstream enhancer in the ...

Antoniv(T T),De Val(S),Wells(D),Denton(C P... J Biol Chem 2001-07-19

...COL1A2) gene. Four strong DNase I-hypersensitive sites (HS2-5) were only detected in fibroblasts, and a weaker one (HS1)...

A COL1A1 Sp1 binding site polymorphism predisposes to osteoporotic fracture b...

Mann(V),Hobson(E E),Li(B),Stewart(T L),Gra... J Clin Invest 2001-05-17

...COL1A2. Finally, the yield strength of bone derived from "Ss" individuals was reduced when compared with bone derived fr...

Molecular anatomy of an intracranial aneurysm: coordinated expression of gene...

Peters(D G),Kassam(A B),Feingold(E),Heidri... Stroke 2001-04-26

...COL1A2, COL6A1, COL6A2, elastin) and genes involved in extracellular matrix turnover (TIMP-3, OSF-2), cell adhesion and ...

Interaction between GC box binding factors and Smad proteins modulates cell l...

Inagaki(Y),Nemoto(T),Nakao(A),Dijke Pt,Kob... J Biol Chem 2001-06-14

...COL1A2 response to TGF-beta, whereas overexpression of Sp1 in hepatocytes increased basal COL1A2 transcription and confe...

Activation of a fibroblast-specific enhancer of the proalpha2(I) collagen gen...

Denton(C P),Zheng(B),Shiwen(X),Zhang(Z),Bo... Arthritis Rheum 2001-05-03

...Col1a2), linked to a 400-bp minimal Col1a2 promoter driving an Escherichia coli beta-galactosidase (LacZ) reporter gene,...

Thirty-three novel COL1A1 and COL1A2 mutations in patients with osteogenesis ...

Ward(L M),Lalic(L),Roughley(P J),Glorieux(... Hum Mutat 2001-08-30

...COL1A2. Two rare triple helical Gly-->Glu substitutions in COL1A2 are also described. In addition, there were six single...

Association of functional microsatellites in the human type I collagen alpha2...

Hata(R),Akai(J),Kimura(A),Ishikawa(O),Kuwa... Biochem Biophys Res Commun 2000-07-17

...COL1A2) for type I collagen, which accumulates excessively in the affected organs. The COL1A2 gene containing a specific...

Ethanol and arachidonic acid increase alpha 2(I) collagen expression in rat h...

Nieto(N),Greenwel(P),Friedman(S L),Zhang(F... J Biol Chem 2000-08-10

...COL1A2 gene by ethanol and AA. Catalase abrogated the increase in COL1A2 mRNA suggesting an H(2)O(2)-dependent mechanism...

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