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T cell activation by autoantigens in multiple sclerosis.

Matsiota-Bernard(P),Roullet(E),Ragimbeau(J... Autoimmunity 1994-08-08

A panel of autoantigens (myosin, actin, myelin basic protein MBP, and thyroglobulin) was used to analyze antigen recogni...

Monoclonal anti-gamma interferon antibodies enhance experimental allergic enc...

Lublin(F D),Knobler(R L),Kalman(B),Goldhab... Autoimmunity 1994-08-08

...MBP and anti-IFN-gamma Mab resulted in more sever disease than that induced by MBP stimulated cells or MBP and IFN-gamma...

Repertoire of rat MBP-reactive T cells: DNA sequencing analysis further demon...

Sun(D),Shah(R),Coleclough(C) Cell Immunol 1994-08-11

...MBP(68-88) as well as those specific for MBP(87-99). We previously reported that such T cells can express a diversity of...

A V lambda x-bearing monoclonal antibody with similar specificity and sequenc...

Maier(C C),Galin(F S),Jarpe(M A),Jackson(P... J Immunol 1994-08-09

The fine specificity of mAb F28C4 to myelin basic protein (MBP), acetyl residues 1-9, has been compared with the previou...

Involvement of protein kinase C in cAMP regulation of myelin basic protein ge...

Anderson(S),Miskimins(R) J Neurosci Res 1994-08-09

...MBP) gene that are responsible for the induction of MBP transcription by cAMP. Using stably transfected cell lines conta...

Myelin basic protein content of aggregating rat brain cell cultures treated w...

Loughlin(A J),Honegger(P),Woodroofe(M N),C... J Neurosci Res 1994-08-09

...MBP. The effect of IFN-gamma on MBP content of cultures was not affected by the presence of macrophages in increased num...

Multiple sclerosis: occurrence of myelin basic protein peptide-reactive T cel...

Fredrikson(S),Söderström(M),Hillert(J),Sun... Acta Neurol Scand 1994-08-08

...MBP, the eight different MBP peptides or AChR. None of the MBP peptides predominated as T cell antigen among the MS pati...

Structural requirements for binding of an immunodominant myelin basic protein...

Wucherpfennig(K W),Sette(A),Southwood(S),O... J Exp Med 1994-02-02

...MBP(84-102) and DRB1 molecules is more immunogenic for MBP reactive T cells. The minimal MBP peptide epitope for several...

Gelatinase B is present in the cerebrospinal fluid during experimental autoim...

Gijbels(K),Proost(P),Masure(S),Carton(H),B... J Neurosci Res 1994-01-28

...MBP) with gelatinase B and analysis of the cleavage products by protein sequence analysis pinpointed two cleavage sites ...

Analysis of the human MBP promoter in primary cultures of oligodendrocytes: p...

Wrabetz(L),Shumas(S),Grinspan(J),Feltri(M ... J Neurosci Res 1994-01-28

...MBP by restricting its expression in other cells. These experiments strongly support using primary cultures of oligodend...

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