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Two-locus linkage analysis in multiple sclerosis (MS).

Tienari(P J),Terwilliger(J D),Ott(J),Palo(... Genomics 1994-06-20

...MBP) on chromosome 18 and the HLA complex on chromosome 6. This set of families provides a unique opportunity to perform...

E-selectin and vascular cell adhesion molecule-1 as critical adhesion molecul...

Wakita(H),Sakamoto(T),Tokura(Y),Takigawa(M... J Cutan Pathol 1994-06-21

...MBP) and eosinophil peroxidase (EPO) were found constantly in acute lesions and only occasionally in chronic lesions. Th...

Clonal expansion and persistence of human T cells specific for an immunodomin...

Wucherpfennig(K W),Zhang(J),Witek(C),Matsu... J Immunol 1994-06-21

...MBP-specific T cell lines were specific for the immunodominant MBP(84-102) and MBP(143-168) peptides and were restricted...

A cross-reactive idiotope on T cells from PL/J mice and Lewis rats that recog...

Zhou(S R),Whitaker(J N),Han(Q),Maier(C),Bl... J Immunol 1994-09-06

...MBP) molecule. We sought the presence of a cross-reactive idiotope (Id) in encephalitogenic T cells of Lewis rats by exa...

Myelin basic protein in the cerebrospinal fluid of patients with brain tumors...

Nakagawa(H),Yamada(M),Kanayama(T),Tsuruzon... Neurosurgery 1994-09-08

...MBP that exceeded the prechemotherapy level. The MBP level decreased or returned to normal in the patients with a good r...

Gamma interferon induces rapid and coordinate activation of mitogen-activated...

Liu(M K),Brownsey(R W),Reiner(N E) Infect Immun 1994-07-20

...MBP) was used as the substrate. Anion-exchange chromatography of high-speed supernatants prepared from detergent extract...

RNA binding by Sxl proteins in vitro and in vivo.

Samuels(M E),Bopp(D),Colvin(R A),Roscigno(... Mol Cell Biol 1994-07-18

...MBP-Sxl fusion protein demonstrated preferential binding to RNAs containing poly(U) tracts, and the protein footprinted ...

Peptide specificity of anti-myelin basic protein antibodies in patients with ...

Sellebjerg(F),Frederiksen(J L),Olsson(T),L... Scand J Immunol 1994-07-19

...MBP peptides. Thirty-two out of 40 patients (80%) with ON had cells in cerebrospinal fluid secreting anti-MBP peptide an...

Expression of the myelin basic protein gene in transgenic mice expressing hum...

Haas(S),Haque(N S),Beggs(A H),Khalili(K),K... Virology 1994-07-15

...MBP levels that parallel the severity of dysmyelination in the corresponding animals. Analysis of MBP RNA by Northern an...

Animal models.

Wekerle(H),Kojima(K),Lannes-Vieira(J),Lass... Ann Neurol 1994-07-28

...MBP) specific EAE in the Lewis rat, the T-cell response is directed against one strongly dominant peptide epitope. The e...

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