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Catalytic cycle of ATP hydrolysis by P-glycoprotein: evidence for formation of …

Sauna(ZE),Kim(IW),Nandigama(K),Kopp(S),Chiba… Biochemistry 2007-12-04

...Pgp (previously demonstrated in the E556Q/E1201Q mutant Pgp) can be obtained with the wild-type protein by use of the no...

Localization of p-glycoprotein mRNA in the tissues of Haemonchus contortus adul…

Smith(JM),Prichard(RK) J Parasitol 2002-06-00

...Pgps) are present in a number of nematode species, including Haemonchus contortus. Allelic variation in some Pgp genes h...

Real-time monitoring of P-glycoprotein activation in living cells.

Landwojtowicz(E),Nervi(P),Seelig(A) Biochemistry 2002-06-25

...Pgp-ATPase activation. They support a Pgp-mediated transport of protons from the site of ATP hydrolysis to the cell surf...

Noninvasive detection of multidrug resistance in patients with hematological ma…

Kostakoglu(L) Clin Lymphoma 2002-03-00

...Pgp and MRP, and has been used to visualize Pgp expression. (99m)Tc-tetrofosmin is also a substrate for the Pgp efflux p...

Functional evidence of multidrug resistance transporters (MDR) in rodent olfact…

Molinas(A),Sicard(G),Jakob(I) PLoS One 2012-00-00

...Pgp or MRP inhibitors. The presence of Pgp or MRP1 encoding genes in the olfactory mucosa of rat and mouse was confirmed...

Pgp and MRP activities using calcein-AM are prognostic factors in adult acute m…

Legrand(O),Simonin(G),Perrot(JY),Zittoun(R),… Blood 1998-06-15

Thirteen cell lines with different levels of Pgp and MRP expression were used to assess the ability of calcein acetoxyme...

Relationship between paclitaxel activity and pathobiology of human solid tumors.

Gan(Y),Wientjes(MG),Au(JL) Clin Cancer Res 1998-12-00

...Pgp), p53, and Bcl-2]. Pgp, p53, and Bcl-2 proteins were detected by immunohistochemical methods. The drug sensitivity r...

Synthetic complementary peptides inhibit a neutrophil chemoattractant found in …

Pfister(RR),Haddox(JL),Blalock(JE),Sommers(C… Cornea 2000-05-00

...PGP. The polarization assay was used to measure the potential chemotactic response of PMNs to synthetic N-acetyl-PGP, th...

Pyroglutamyl peptidase type I from Trypanosoma brucei: a new virulence factor f…

Morty(RE),Bulau(P),Pellé(R),Wilk(S),Abe(K) Biochem J 2006-03-15

...PGP (pyroglutamyl peptidase), belonging to the C15 family of cysteine peptidases. We showed that PGP is expressed in all...

Multidrug-resistance phenotype and clinical responses to gemtuzumab ozogamicin.

Linenberger(ML),Hong(T),Flowers(D),Sievers(E… Blood 2001-08-15

...Pgp surface expression and Pgp function using a dye efflux assay. In most cases, surface expression of Pgp correlated wi...

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