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The inflammatory lesion of T cell line transferred experimental autoimmune en...

Lannes-Vieira(J),Gehrmann(J),Kreutzberg(G ... Acta Neuropathol 1994-09-15

...MBP)-reactive, or MBP-reactive but non-encephalitogenic T cell lines. All the MBP-specific T cell lines predominantly us...

Isolation and characterization of mutants of human mitogen-activated protein ...

Krishnan(I S),Kovacs(E D),Sass(P M) FEBS Lett 1994-11-23

...MBP). Five classes of mutants have been isolated. The first class of mutants comprises of G30A/G32A, A50D and R65A/R68A/...

Regulation of experimental autoimmune encephalomyelitis: inhibition of adopti...

Varriale(S),Béraud(E),Barbaria(J),Galibert... J Neuroimmunol 1994-09-28

...MBP T cell line cells. The present investigations were undertaken in order to lend support to the hypothesis that RASC p...

Differentiation of oligodendrocytes cultured from developing rat brain is enh...

Yim(S H),Farrer(R G),Hammer(J A),Yavin(E),... J Neurosci Res 1994-11-16

...MBP) was not affected. Although the overall effect of added GM3 was to decrease the phosphorylation of most proteins in ...

Interleukin-8 activates microtubule-associated protein 2 kinase (ERK1) in hum...

Van Lint(J),Van Damme(J),Billiau(A),Merlev... Mol Cell Biochem 1994-10-31

...MBP) and the MBP-derived peptide APRTPGGRR patterned after the specific concensus sequence in MBP for ERK enzymes. The a...

Antigenic peptide binding to MHC class II molecules at increased peptide conc...

Nag(B),Mukku(P V),Arimilli(S),Phan(D),Desh... Mol Immunol 1994-11-18

...MBP (83-102)Y83 were selected for this study. The on-rate kinetic results showed saturation of MHC class II occupancy at...

Optic neuritis and multiple sclerosis: the T cell repertoires to myelin prote...

Söderström(M),Link(H),Fredrikson(S),Sun(J ... Acta Neurol Scand 1994-11-17

...MBP), proteolipid protein (PLP) and MBP peptides have been described in multiple sclerosis (MS) and optic neuritis (ON),...

The distribution of inflammatory demyelinated lesions in the central nervous ...

Meeson(A P),Piddlesden(S),Morgan(B P),Reyn... Exp Neurol 1994-12-20

...MBP), or MBP-specific T-lymphocytes, is primarily an inflammatory condition of the central nervous system (CNS) with lit...

Lysis of rat brain microvascular endothelial cells mediated by resting but no...

Engelhardt(B),Görlach(H),Risau(W),Wekerle(... J Neuroimmunol 1994-12-28

...MBP)-specific T cells is inseparably associated with their cytotoxic potential. MBP-specific T cells lyse all cells that...

HLA restriction and TCR usage of T lymphocytes specific for a novel candidate...

Voskuhl(R R),Robinson(E D),Segal(B M),Tran... J Immunol 1994-12-07

...MBP (X2 MBP), a sequence included in the 21.5- and 20.2-kDa isoforms of MBP. These cells were shown to be CD4+, HLA clas...

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