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An anionic cyanine probe with enhanced ROS-stability for butylcholinesterase ...

Li(J),Zhang(Z),Xu(S),Liu(H),Pan(W),Yan(M) Chem Commun (Camb) 2026-06-29

...BChE probe targeting butyrylcholinesterase (BChE) was developed using an anionic cyanine dye (ACy5-QL) with 762 nm emiss...

Targeting Metabolic and Neurodegenerative Enzymes With Cousinia cirsioides Bo...

Ceyhan(HŞ),Paşayeva(L),Fatullayev(H),İnce(... Chem Biodivers 2026-06-00

...BChE), and tyrosinase. Antioxidant capacities were evaluated using DPPH, ABTS, FRAP, and CUPRAC assays. TPC, TFC and LC-...

Rational design of an environment-sensitive fluorescent probe for monitoring ...

Guo(N),Wang(F),Wang(Y),Du(J),Zhang(Q),Cao(... RSC Med Chem 2026-06-17

...BChE inhibitor pharmacophore as the recognition and therapeutic moiety. LY36 exhibits high selectivity for BChE over ace...

Mediterranean Asteraceae as Natural Sources of Antioxidants and Enzyme Inhibi...

Hammami(N),Rodrigues(MJ),Fernandes(E),Steg... Chem Biodivers 2026-06-00

...BChE (IC50  = 8.63 mg/mL). No cytotoxicity was detected at 100 µg/mL in human hepatocarcinoma (HepG2), neuroblastoma (SH...

Perillaldehyde-derived chromeno-dipyrimidines as multi-target-directed ligand...

Bazine(I),Maadadi(R),Derbal(S),Litim(B),Ai... Eur J Med Chem 2026-10-05

...BchE, supported by their calculated docking scores. The findings from the docking analysis were further confirmed by 100...

Studies of design, synthesis and biological properties, ADMET profiling, mole...

He(ZX),Lin(ZQ),Liu(YX),Wang(SH),Lin(L),Gua... Bioorg Chem 2026-09-05

...BChE), and anti- inflammatory effects. The IC50 values were 73.65 ± 3.50 μM, 88.20 ± 9.56 μM and 31.42 ± 1.91 μM, respec...

Investigation of the enzyme-inhibitory, antibacterial, and anticancer propert...

Topal(M),Topal(F),Yilmaz(F),Bulut Atalay(E... Turk J Chem None

...BChE. Dual inhibition of AChE and BChE by these compounds may be promising for addressing cholinergic deficits associate...

Bioactivity assessment and LC-MS/MS-based phenolic characterization of Gypsop...

Açıkgöz(A),Türkmen(M),Koçer(O),Uysal(İ),Se... Sci Rep 2026-05-22

...BChE), with IC₅₀ values of 160.163 ± 2.155 µg/mL and 223.903 ± 1.049 µg/mL, respectively. The antiproliferative activity...

Novel Donepezil-Chalcone Hybrids as Potential Multifunctional Anti-Alzheimer'...

Lin(Z),Jiang(Z),Chen(D),Liu(Y),He(Z),Ning(... Chem Biol Drug Des 2026-05-00

...BChE. Subsequently, a subset of these derivatives was investigation to inhibit Aβ1-42 aggregation and promote Aβ1-42 dis...

Promising Flavonoid-Fused Aminoquinolines as Synthetic Alzheimer's Disease Mo...

Rocha(IO),Delgado(CP),Nogara(PA),Rocha(JBT... Chembiochem 2026-05-27

...BChE inhibitory activity and subjected to molecular docking studies. In vitro cholinesterase assays and in silico dockin...

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