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PARK19 truncation mutant Dnajc6 causes lysosomal deficiency-induced upregulat...

Wang(HL),Chen(YL),Chiu(TJ),Chiu(CC),Weng(Y... NPJ Parkinsons Dis 2026-03-12

...Jun/ATF-2 and RIPK1-RIPK3-MLKL death cascades. Our results suggest that PARK19 (Q789X) DNAJC6 mutation causes lysosomal ...

Ferulic acid promotes hair growth via estrogen receptor alpha activation in c...

Rim(H),Kim(J),Joo(JH),Kim(SH),Choi(YH),Shi... Sci Rep 2026-03-12

...JUN mRNA expression, indicating estrogen-like ERα activation, and increased the expression of MAPK pathway-associated pr...

ANKRD49 promotes the epithelial-mesenchymal transition of non-small cell lung...

Yuan(M),Qin(GM),Zhang(CL),Liu(CF),Liang(G)... Cancer Cell Int 2026-03-12

...Jun/MMP pathways. Although epithelial-mesenchymal transition (EMT) is critical for tumor dissemination, the role of ANKR...

Maternal obesity induces activator protein 1-mediated inflammatory response t...

Chen(LW),Hossain(MN),Gao(Y),Kou(Z),Islam(S... J Physiol 2026-04-00

...Jun and Jund. Single-cell ATAC sequencing revealed the activator protein 1 (AP-1) binding sites in the promoter regions ...

Tumor-Derived Exosomal TAGLN2 Promotes Metastasis by Inducing Vascular Permea...

Yu(S),Zhuo(J),Hong(X),Rao(S),Ye(Y),Kang(D)... Adv Sci (Weinh) 2026-05-00

...junctions. In vivo, exosomal TAGLN2 accelerated tumor growth and lung metastasis by generating abnormal, leaky vasculatu...

Parbendazole induces semaphorin 3A expression via JNK/c-Jun signaling pathway...

Fujita(M),Kamata(Y),Tanemoto(N),Morita(M),... J Dermatol Sci 2026-05-00

...Jun-N-terminal kinase (JNK) and c-Jun was analyzed by western blotting. Parbendazole dose-dependently increased Sema3A g...

Combining network Pharmacology, molecular Simulation, and animal experiments ...

Huang(R),Yu(S),Xu(W),Tao(W) In Silico Pharmacol None

...JUN, TP53, AKT1) were enriched in xenobiotic response, oxidative stress, and inflammation. KEGG pathways included IBS-D/...

An integrated metabolomics and network pharmacology approach to reveal the an...

Chen(P),Dong(S),Chu(L),Zhang(L),Qin(W) Food Chem X 2026-04-00

...JUN, EP300, and ESR1-were strongly correlated with antioxidant activity. On the basis of topological and Pearson correla...

c-Jun in neurodegeneration: A key transcriptional regulator with therapeutic ...

Khan(FA),Khan(H),Awan(UA),Nurahmat(M),Nabi... Mol Ther Nucleic Acids 2026-06-16

...Jun-via small-molecule inhibitors (e.g., SP600125), RNA interference, or modulation of upstream c-Jun N-terminal kinase ...

FAK/SRC-JNK axis promotes ferroptosis via upregulating ACSL4 expression.

Qin(J),Ma(S),Wang(J),Huang(S),Luan(J),He(J... Cell Death Dis 2026-03-20

...Jun, STAT3, ELK1, and HSF1, inhibit ferroptosis by binding to the ACSL4 promoter and repressing its expression. The net ...

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