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Structural analysis of multiprotein complexes by cross-linking, mass spectrom...

Maiolica(Alessio),Cittaro(Davide),Borsotti... Mol Cell Proteomics 2008-05-30

...NDEL1 homodimer and the NDC80 heterotetramer. An important limitation of the cross-linking approach, so far, was the ide...

Dissecting DISC1 function through protein-protein interactions.

Brandon(N J) Biochem Soc Trans 2008-02-05

...Ndel1 (nudE nuclear distribution gene E homologue-like 1), an enigmatic protein which may have diverse functions as both...

Cenp-F links kinetochores to Ndel1/Nde1/Lis1/dynein microtubule motor complexes.

Vergnolle(Maïlys A S),Taylor(Stephen S) Curr Biol 2008-01-02

...Ndel1, Nde1, and Lis1 localize to kinetochores in a Cenp-F-dependent manner. In addition, Nde1, but not Ndel1, is requir...

DISC1, PDE4B, and NDE1 at the centrosome and synapse.

Bradshaw(Nicholas J),Ogawa(Fumiaki),Antoli... Biochem Biophys Res Commun 2008-12-16

...NDEL1), LIS1, and phosphodiesterases 4B and 4D (PDE4B and PDE4D). We demonstrate that NDE1, NDEL1 and LIS1, together wit...

Lissencephaly and LIS1: insights into the molecular mechanisms of neuronal mi...

Wynshaw-Boris(A) Clin Genet 2007-11-07

...NDEL1, is a phosphoprotein that is a substrate for CDK5 (or CDK2 in fibroblasts) and Aurora-A, two mitotic kinases. CDK5...

Disrupted-In-Schizophrenia 1 regulates integration of newly generated neurons...

Duan(Xin),Chang(Jay H),Ge(Shaoyu),Faulkner... Cell 2007-11-01

...NDEL1 in regulating adult neurogenesis. Taken together, our study identifies DISC1 as a key regulator that orchestrates ...

Genetic interactions among cortical malformation genes that influence suscept...

Locke(Cody J),Williams(Shelli N),Schwarz(E... Brain Res 2007-01-23

...NDEL1. Phenotypic analysis of animals targeted by RNA interference (RNAi) was performed using a pentylenetetrazole (PTZ)...

Role of DISC1 in neural development and schizophrenia.

Mackie(Shaun),Millar(J Kirsty),Porteous(Da... Curr Opin Neurobiol 2007-04-25

...NDEL1 during neurodevelopment and with the phosphodiesterase PDE4B in neuronal cell signalling. Thus, DISC1 and its path...

NDEL1 phosphorylation by Aurora-A kinase is essential for centrosomal maturat...

Mori(Daisuke),Yano(Yoshihisa),Toyo-oka(Kaz... Mol Cell Biol 2007-01-18

...NDEL1 at Ser251 at the beginning of mitotic entry. Interestingly, NDEL1 phosphorylated by Aurora-A was rapidly downregul...

Recruitment of katanin p60 by phosphorylated NDEL1, an LIS1 interacting prote...

Toyo-Oka(Kazuhito),Sasaki(Shinji),Yano(Yos... Hum Mol Genet 2006-06-05

...NDEL1. We demonstrate that phosphorylation of NDEL1 by Cdk5 facilitates interaction between NDEL1 and p60, suggesting th...

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