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Structural determinants within Pbx1 that mediate cooperative DNA binding with p…

Lu(Q),Kamps(M P) Mol Cell Biol 1996-07-29

...Pbx2 and Pbx3 and predicted to form an alpha-helix, enhances monomeric DNA binding by Pbx1 and also contributes to maxim...

Three genes in the human MHC class III region near the junction with the class …

Sugaya(K),Fukagawa(T),Matsumoto(K),Mita(K),T… Genomics 1995-02-24

...PBX2 homeobox gene designated HOX12, and the human counterpart of the mouse mammary tumor gene int-3 were found. The con...

The novel gene G17, located in the human major histocompatibility complex, enco…

Aguado(B),Campbell(R D) Genomics 1995-06-29

...PBX2)-Met (G17) substitution at amino acid 393 near the C-terminus. The PBX2 gene was originally localized only to human...

Selection and application of human single chain Fv antibody fragments from a se…

de Kruif(J),Boel(E),Logtenberg(T) J Mol Biol 1995-05-26

...PBX2. The functional capacity of monoclonal phage antibodies was assessed in immuno-histochemical staining of tissue spe...

The hexapeptide LFPWMR in Hoxb-8 is required for cooperative DNA binding with P…

Neuteboom(S T),Peltenburg(L T),van Dijk(M A)… Proc Natl Acad Sci U S A 1995-10-27

...Pbx2. Hox gene products contain a highly conserved hexapeptide connected by a linker of variable length to the homeodoma...

Hox gene products modulate the DNA binding activity of Pbx1 and Pbx2.

van Dijk(M A),Peltenburg(L T),Murre(C) Mech Dev 1995-12-06

...Pbx2 and Pbx3. We show here that two members of this family, Pbx1 and Pbx2 bind cooperatively to DNA with both Hoxb-7 an...

Localization of Pbx1 transcripts in developing rat embryos.

Roberts(V J),van Dijk(M A),Murre(C) Mech Dev 1995-11-03

...Pbx2 and Pbx3. The Pbx family has been shown to modulate the biological activities of the Hox proteins. We demonstrate h...

Fusion with E2A converts the Pbx1 homeodomain protein into a constitutive trans…

Lu(Q),Wright(D D),Kamps(M P) Mol Cell Biol 1994-06-24

...PBX2 and PBX3 genes, bind the DNA sequence ATCAATCAA. E2A-Pbx1 strongly activates transcription in vivo through this mot...

Transformation properties of the E2a-Pbx1 chimeric oncoprotein: fusion with E2a…

Monica(K),LeBrun(D P),Dedera(D A),Brown(R),C… Mol Cell Biol 1994-12-20

...Pbx2 and Pbx3 were also transformation competent, demonstrating that all known members of this highly similar subfamily ...

Fusion with E2A alters the transcriptional properties of the homeodomain protei…

LeBrun(D P),Cleary(M L) Oncogene 1994-06-14

...PBX2 or PBX3. Using a binding site selection assay, we identified a consensus nucleotide sequence ATCAATCA specifically ...

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