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Response to MLN8237 in pancreatic cancer is not dependent on RalA phosphoryla...

Neel(Nicole F),Stratford(Jeran K),Shinde(V... Mol Cancer Ther 2014-09-29

...RalA-targeted therapy for PDAC. We used a site-specific phospho-S194 RalA antibody and determined that RalA S194 phospho...

RalR (a DNase) and RalA (a small RNA) form a type I toxin-antitoxin system in...

Guo(Yunxue),Quiroga(Cecilia),Chen(Qin),McA... Nucleic Acids Res 2014-08-04

...RalA antitoxin activity and appears to stabilize RalA. Also, RalR/RalA is beneficial to the Escherichia coli host for re...

Sec5 and Exo84 mediate distinct aspects of RalA-dependent cell polarization.

Hazelett(C Clayton),Yeaman(Charles) PLoS One 2013-03-21

...RalA and its effectors in the Exocyst complex as directly necessary for migration and invasion of prostate cancer tumor ...

Genetic deletion of RALA and RALB small GTPases reveals redundant functions i...

Peschard(Pascal),McCarthy(Afshan),Leblanc-... Curr Biol 2013-05-23

...RALA and RALB: RALA has been implicated in epithelial cell polarity [2], insulin secretion [3], GLUT4 translocation [4, ...

Role of RalA downstream of Rac1 in insulin-dependent glucose uptake in muscle...

Nozaki(Shinsuke),Ueda(Shuji),Takenaka(Nobu... Cell Signal 2013-01-09

...RalA has been implicated in glucose uptake in insulin-stimulated adipocytes, although it remains unclear whether RalA ha...

Differential involvement of RalA and RalB in colorectal cancer.

Martin(Timothy D),Der(Channing J) Small GTPases 2013-04-03

...RalA and RalB activation in CRC tumor cell lines and tumors. Surprisingly we found antagonistic roles for RalA and RalB ...

PGE2 promotes renal carcinoma cell invasion through activated RalA.

Li(Z),Zhang(Y),Kim(W J),Daaka(Y) Oncogene 2013-04-30

...RalA and Ral·GTP inactivator RGC2. The results support the idea that targeted interference of EP2/EP4 signal to RalA·GTP...

Ral GTPases in tumorigenesis: emerging from the shadows.

Kashatus(David F) Exp Cell Res 2013-10-25

...RalA and RalB, remains the most poorly understood. This review will focus on key developments in our understanding of Ra...

Identification and characterisation of the RalA-ERp57 interaction: evidence f...

Brymora(Adam),Duggin(Iain G),Berven(Leise ... PLoS One 2013-05-28

...RalA and ERp57, an oxidoreductase and signalling protein. ERp57 bound specifically to the GDP-bound form of RalA, but no...

LST1 promotes the assembly of a molecular machinery responsible for tunneling...

Schiller(Christian),Diakopoulos(Kalliope N... J Cell Sci 2013-10-22

...RalA to the plasma membrane and promoting its interaction with the exocyst complex. Furthermore, we determined that LST1...

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