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ZFP36 Alleviates MASLD Through Facilitating TEAD4 mRNA Degradation After Sleeve…

Tang(Z),Sun(M),Chen(J),Shi(B),Yu(T),Hu(S) Int J Mol Sci 2026-04-22

...TEAD4 mRNA to promote its degradation, thereby modulating the Hippo pathway. Inhibition of TEAD4 transcriptional activit...

Development of a TEAD-independent reporter system for specific and sensitive me…

Zhang(J),Yang(W),Yuan(Q),Huang(F),Lv(D),Zhan… Biochim Biophys Acta Mol Cell… 2026-03-00

...TEAD4, with the native TEAD DNA-binding domain (TEA) removed. Structural modeling of the G-TEAD4(217) fusion protein con...

Overexpression of TEAD4 in atypical teratoid/rhabdoid tumor: New insight to the…

Suzuki(M),Kondo(A),Ogino(I),Arai(H),Tomita(T… Pediatr Blood Cancer 2017-07-00

...TEAD4 and YAP1 overexpression in all samples. Cell proliferation and migration were significantly reduced in TEAD4-mutat...

TEAD4 Transcriptionally Activates TRIB3 to Induce Ferroptosis Resistance throug…

Wang(J),Wu(X) Gut Liver 2025-07-15

...TEAD4TRIB3-TEAD4 targeting. We also employed colony formation assays to analyze cell proliferation, flow cytometry to me...

Screening of peptide inhibitors targeting YAP-TEAD4 interaction: affinity evalu…

Yang(X),Yang(S),Lin(G),Chen(S),Jiang(H),Wang… J Enzyme Inhib Med Chem 2026-12-00

...TEAD4. MD simulations further demonstrated that peptide-4 stably bound to the TEAD4. MTT assays showed that peptide-4 su...

VGLL4 targets a TCF4-TEAD4 complex to coregulate Wnt and Hippo signalling in co…

Jiao(S),Li(C),Hao(Q),Miao(H),Zhang(L),Li(L),… Nat Commun 2017-00-04

...TEAD4 associates with TCF4 to form a complex and cobind target genes. VGLL4 targets this TEAD4-TCF4 complex to interfere...

Regulation of energy metabolism during early mammalian development: TEAD4 contr…

Kumar(RP),Ray(S),Home(P),Saha(B),Bhattachary… Development 2018-00-01

...TEAD4, which is essential for pre-implantation mammalian development, regulates this process by promoting mitochondrial ...

A Four-Gene Prognostic Signature Based on the TEAD4 Differential Expression Pre…

Gong(X),Li(N),Sun(C),Li(Z),Xie(H) Front Pharmacol 2022-00-00

...TEAD4 was found to be significantly correlated with poor prognosis in LUAD-patients. A total of 102 DEGs in TEAD4-high v...

Discovering TEAD4 modulators for hepatocellular carcinoma: a GAN-enabled genera…

Premnath(V),Karuppasamy(R),Kaliappan(J),Veer… Front Bioinform None

...TEAD4 modulators, supporting TEAD4 targeted drug discovery across liver diseases.

Expression of Hippo Pathway Molecules in Distal Bile Duct Cancer.

Lee(KR),Hong(SA),Hong(M),Kim(JY) Appl Immunohistochem Mol Morp… 2025-09-01

...TEAD4) are primary Hippo pathway components. We evaluated LATS1/2, YAP, and TEAD4 expression and their correlation with ...

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