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Defective processing and trafficking of water channels in nephrogenic diabete...

Kamsteeg(E J),Deen(P M),van Os(C H) Exp Nephrol 2000-11-01

...AQP2) are the cause of the autosomal recessive and autosomal dominant forms of NDI. Mutant AQP2 proteins, found in autos...

Cloning and functional expression of human aquaporin8 cDNA and analysis of it...

Koyama(N),Ishibashi(K),Kuwahara(M),Inase(N... Genomics 1999-01-07

...AQP2 and AQP3 are 28.9 and 29.5% identical to human AQP8, respectively. The human AQP8 is only 74.9% identical to rat AQ...

Decreased aquaporin-2 expression and apical plasma membrane delivery in kidne...

Earm(J H),Christensen(B M),Frøkiaer(J),Mar... J Am Soc Nephrol 1999-04-19

...AQP2 downregulation and reduced apical plasma membrane delivery of AQP2 play important roles in the development of polyu...

Bidirectional water fluxes and specificity for small hydrophilic molecules in...

Meinild(A K),Klaerke(D A),Zeuthen(T) J Biol Chem 1999-01-08

...AQP2: 1, 0.8, 1, 1; AQP3: 1, 0.2, 0.7, 0.4; AQP4: 1, 0.9, 1, 1; and AQP5: 1, 1, 1, 0.8. As seen there is no clear connec...

Select types of supporting cell in the inner ear express aquaporin-4 water ch...

Takumi(Y),Nagelhus(E A),Eidet(J),Matsubara... Eur J Neurosci 1999-01-14

...AQP2, 3 or 5. Immunofluorescence and postembedding immunogold labelling revealed a strictly non-epithelial distribution ...

Vasopressin receptor mutations causing nephrogenic diabetes insipidus.

Bichet(D G),Turner(M),Morin(D) Proc Assoc Am Physicians 1999-01-15

...AQP2 gene that codes for the vasopressin-dependent water channel. A majority (> 90%) of congenital nephrogenic diabetes ...

Disordered water channel expression and distribution in acquired nephrogenic ...

Marples(D),Frøkiaer(J),Knepper(M A),Nielse... Proc Assoc Am Physicians 1999-01-15

A series of recent studies have demonstrated that expression of aquaporin-2 (AQP2), the vasopressin-regulated water chan...

Recent advances in the understanding of water metabolism in heart failure.

Schrier(R W),Martin(P Y) Adv Exp Med Biol 1999-03-10

...AQP2), located in the collecting duct cells has been shown in experimental heart failure. This AQP2 upregulation can be ...

Lessons on renal physiology from transgenic mice lacking aquaporin water chan...

Verkman(A S) J Am Soc Nephrol 1999-06-22

...AQP2, AQP3, and AQP4 in the collecting duct; AQP6 in the papilla; and AQP7 in the proximal tubule. AQP2 is the vasopress...

An impaired routing of wild-type aquaporin-2 after tetramerization with an aq...

Kamsteeg(E J),Wormhoudt(T A),Rijss(J P),va... EMBO J 1999-06-28

...AQP2 forms homotetramers. When expressed in oocytes, wild-type AQP2 and AQP2-E258K also formed homotetramers, whereas AQ...

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