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Oncogenic fingerprint of epidermal growth factor receptor pathway and emergin...

Sobani(Zain A),Sawant(Ashwin),Jafri(Mikram... World J Clin Oncol 0000-00-00

...KRAS)-mutant patients led to the restriction of anti-EGFR antibodies to KRAS wild-type patients by Food and Drug Adminis...

Quantitative assessment of pancreatic cancer precursor lesions in IHC-stained...

Aeffner(Famke),Martin(Nathan T),Peljto(Mir... Lab Invest 0000-00-00

...Kras; Trp53; Pdx-Cre (KPC) mice, a validated model of PDAC development. tIA profiling of training regions of PanIN and t...

In vivo oncogenic conflict triggered by co-existing KRAS and EGFR activating ...

Ambrogio(C),Barbacid(M),Santamaría(D) Oncogene 0000-00-00

Activating mutations in KRAS and EGFR, the two most frequent oncogenes in human lung adenocarcinoma, are mutually exclus...

Efficacy, Tolerability, and Biomarker Analyses of Once-Every-2-Weeks Cetuxima...

Cheng(Ann-Lii),Cornelio(Gerardo),Shen(Lin)... Clin Colorectal Cancer 0000-00-00

In patients with KRAS wild-type (wt) metastatic colorectal cancer (mCRC), outcomes with first-line chemotherapies are im...

Heterogeneity of acquired resistance to anti-EGFR monoclonal antibodies in pa...

Pietrantonio(Filippo),Vernieri(Claudio),Si... Clin Cancer Res 0000-00-00

...KRAS, NRAS and EGFR extracellular domain mutations as well as HER2/MET alterations. However, these findings derive from ...

KRAS-mutation status dependent effect of zoledronic acid in human non-small c...

Kenessey(István),Kói(Krisztina),Horváth(Or... Oncotarget 0000-00-00

...KRAS-mutant human NSCLC cell lines showed resistance to zoledronic acid wild-type KRAS-cells proved to be sensitive. Com...

[Research progress of serrated polyposis syndrome].

Dong(Shihao),Chen(Jingsong) Zhonghua Wei Chang Wai Ke Z... 0000-00-00

...KRAS gene, which induces colorectal cancer through the RAS-RAF-MAPK signaling pathway, is often found in SPS as well as ...

Targeted delivery of chemotherapy using HSP90 inhibitor drug conjugates is hi...

Bobrov(Egor),Skobeleva(Natalia),Restifo(Di... Oncotarget 0000-00-00

...KRAS and TP53 cancer genes. Poor tumor tissue penetration is the major source of resistance in pancreatic cancer where c...

Adaptation of a RAS pathway activation signature from FF to FFPE tissues in c...

Omolo(Bernard),Yang(Mingli),Lo(Fang Yin),S... BMC Med Genomics 0000-00-00

The KRAS gene is mutated in about 40 % of colorectal cancer (CRC) cases, which has been clinically validated as a predic...

Spatio-temporal mutation profiles of case-matched colorectal carcinomas and t...

Kovaleva(Valentina),Geissler(Anna-Lena),Lu... Mol Cancer 0000-00-00

...KRAS exon 2; 1/9 NRAS Exon 3) of cases. RAS mutation status was maintained in case-matched metastases throughout the dis...

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