...KRAS (rs61764370) and VEGFA (rs3025039). Meta-analysis yielded nominal significance (at α=0.05) for rs4444903 and rs1154...
...KRAS and RHOA, respectively. In addition to mutations directly affecting the GTPase pathway, TCR signaling mutations ind...
...KRAS alleles and isogenically-matched derivative cell lines, DKO-1 (mutant KRAS allele only) and DKs-8 (wild-type KRAS a...
...KRAS mutations. The frequency of KRAS mutation was not associated with age, gender, or smoking history. The number of pa...
...KRAS mutations. A total of 121 mutations in EGFR or KRAS were detected. 75 pts had a sensitizing EGFR mutation. (RR = 63...
...KRAS mutations, p16 and APC gene promoter methylation.,Pemetrexed 500 mg/m day 1 with ABI 007 260 mg/m is feasible and w...
...KRAS, within the phase I study are reported.,NSCLC pts (n=42) received PF 16 mg (n=1), 30 mg (n=2), 45 mg, the MTD (n=33...
...KRAS gene mutations. MEK1/2 inhibition block the Raf/MEK/ERK pathway since these kinases lie downstream of Ras, and ERK1...
...KRAS mutation status.,In general, the population with tissue available for KRAS analysis (n=233) was representative of t...
...KRAS mutation analysis.,In Arm A, 45 pts were randomized: 19 pts (42%) were KRAS wt, 19 pts (42%) were KRAS mt, and 7 pt...
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