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Spectrum of Gene Mutations in Colorectal Cancer: Implications for Treatment.

Dienstmann(Rodrigo),Tabernero(Josep) Cancer J 0000-00-00

...KRAS and NRAS mutations define a population refractory to anti-epidermal growth factor receptor (EGFR) antibodies, eithe...

PanIN-associated pericyte, glial, and islet remodeling in mice revealed by 3D...

Lin(Pei-Yu),Peng(Shih-Jung),Shen(Chia-Ning... Am J Physiol Gastrointest L... 0000-00-00

...Kras(G12D) mutation were used to develop 3D duct lesion histology. Deep-tissue, tile-scanning microscopy was performed t...

Oncogenic KRAS and BRAF Drive Metabolic Reprogramming in Colorectal Cancer.

Hutton(Josiah E),Wang(Xiaojing),Zimmerman(... Mol Cell Proteomics 0000-00-00

...KRAS G13D to KRAS wild type protein. A study of 8 KRAS wild type and 8 KRAS mutant human colon tumors confirmed the asso...

Optimized Multiplex Detection of 7 KRAS Mutations by Taqman Allele-Specific q...

Orue(Andrea),Rieber(Manuel) PLoS One 0000-00-00

...KRAS somatic mutations with concomitant amplification of non-mutated KRAS in tumor cells and tissues from CRC patients. ...

Synthesis of Clickable Coating Polymers by Postpolymerization Modification: A...

Sola(Laura),Damin(Francesco),Gagni(Paola),... Langmuir 0000-00-00

...KRAS mutation.

Assessment of Pharmacokinetic Interaction Between Capecitabine and Cetuximab ...

Rachar(Veronika),Czejka(Martin),Kitzmuelle... Anticancer Res 0000-00-00

...KRAS wild-type colorectal cancer were randomized into two arms and received either CCB alone (1,000 mg/m(2) bid p.o.), f...

Prediction of KRAS Mutation in Rectal Cancer Using MRI.

Shin(Yu Ri),Kim(Kyung Ah),Im(Soyoung),Hwan... Anticancer Res 0000-00-00

...KRAS mutation evaluation following surgery. Two reviewers assessed diverse MRI findings associated with rectal cancer.,K...

Efficacy and Toxicity of Panitumumab After Progression on Cetuximab and Predi...

Kiss(Igor),Mlcochova(Jitka),Bortlicek(Zbyn... Anticancer Res 0000-00-00

...KRAS mCRC patients, enrolled into the nationwide Czech registry CORECT between January 2007 and December 2012, were scre...

Recurrent mutations of MAPK pathway genes in multiple myeloma but not in amyl...

Kim(Seok Jin),Shin(Hyun-Tae),Lee(Hae-Ock),... Oncotarget 0000-00-00

...KRAS (26%, 6/23) and BRAF (22%, 5/23). However, no significant mutations were found in the 12 patients with AL amyloidos...

Hes1 Controls Exocrine Cell Plasticity and Restricts Development of Pancreati...

Hidalgo-Sastre(Ana),Brodylo(Roxanne L),Lub... Am J Pathol 0000-00-00

...Kras-driven PDAC development. We show that, although pancreatic development is not perturbed on the deletion of Hes1, te...

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