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Epidermal growth factor receptor mutations and gene amplification in Japanese...

Kawaguchi(T),Sasaki(H),Kawahara(M),Takeuch... J Clin Oncol 0000-00-00

...KRAS (exon 1). Gene amplification for EGFR was analyzed by quantitative real-time PCR. HPV was detected by PCR and in-si...

KRAS mutation analysis in patients (pts) with locally advanced pancreatic can...

Chen(H),Raben(D),Schefter(T),Kane(M),McCar... J Clin Oncol 0000-00-00

...KRAS mutations (over 90%). This pilot study evaluated plasma KRAS mutations for disease monitoring in LAPC pts treated o...

Rash severity and dose in phase I dose escalation cetuximab (C225) trial.

Sangha(R S),Ho(C),Beckett(L),Tanaka(M),Lau... J Clin Oncol 0000-00-00

...KRAS mutation (pancreas, PD), 1 of 8 had EGFR amplification by FISH (heavily pre-treated breast, SD). Additional planned...

Associations between the EGFR status as well as KRAS mutations and clinical o...

Stoehlmacher(J),Goekkurt(E),Arnold(D),Keil... J Clin Oncol 0000-00-00

...KRAS mutations (codon 12, 13) were detected in 9/31 (29%) pts. Disease control at 8 weeks was seen in 41% of pts with KR...

Randomized phase III study of capecitabine, oxaliplatin, and bevacizumab with...

Punt(C J),Tol(J),Rodenburg(C J),Cats(A),Cr... J Clin Oncol 0000-00-00

...KRAS in relation to outcome of treatment. No significant financial relationships to disclose.

Mutations of the p53 gene and microsatellite inestability (MSI) as prognostic...

Calvo(B),Fuente(N),Aresti(U),Jangi(M S),Ca... J Clin Oncol 0000-00-00

...Kras mutations using different biological techniques, and mutations of the p53 gene (exons 5 to 9) by sequence analysis....

Reflex testing of lung adenocarcinomas for EGFR and KRAS mutations: The Memor...

Zakowski(M F),Ladanyi(M),Rekhtman(N),Park(... J Clin Oncol 0000-00-00

...KRAS mutations. The presence of a KRAS mutation contraindicates EGFR TKI therapy indicating other agents, or investigati...

VEGF-D expression and EGFR mutations in non-small-cell lung carcinoma.

Wang(Z),Wu(Y),Guo(A),Chen(Z),Su(J),Huang(Y... J Clin Oncol 0000-00-00

...KRAS gene mutation ratio was 12.7% (7/55). Inverse relationship between KRAS and EGFR mutations in the non-small-cell lu...

Comparison of CISH and FISH for detection of EGFR copy number in lung adenoca...

Varella-Garcia(M),Ladanyi(M),Kris(M G),Li(... J Clin Oncol 0000-00-00

...KRAS mutation. No other KRAS mutant case was scored as EGFR-amplified by either method. EGFR was positive by IHC in 28 c...

Insuline like growth factor receptor-1 (IGFR-1), MET, and BRAF and primary re...

Finocchiaro(G),Cappuzzo(F),Rossi(E),Toschi... J Clin Oncol 0000-00-00

...KRAS mutations cannot account for all resistant cases. Preclinical data suggested that MET could interfere with anti-EGF...

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