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TP53 BRCA1 CRISPR single-cell cancer

Kurup(A),Burns(M),Dropcho(S),Pao(W),Loehre... J Clin Oncol 0000-00-00

...KRAS2 exon 2).,All 26 pts were evaluated for response and toxicity. There were 0 CRs, 1 PR (response duration = 5 months...

Hussain(S),Zakowski(M F),Kris(M G),Ladanyi... J Clin Oncol 0000-00-00

...KRAS mutations, response to TKI, and survival and correlated these findings with histology as above.,NSCLC were classifi...

Jayasekara(Harindra),MacInnis(Robert J),Wi... Int J Cancer 0000-00-00

...KRAS+ (HR = 1.07, 95% CI: 1.00-1.15) and BRAF-/KRAS- (HR = 1.05, 95% CI: 1.00-1.11) but not BRAF+ tumors (HR = 0.89, 95%...

Tazi(El Mehdi),Essadi(Ismail),Boutayeb(Sab... Gastroenterology Res 0000-00-00

...KRAS populations. A better understanding of mechanisms of action of drugs, tumor biology, and predictive biomarkers are ...

Dumartin(L),Alrawashdeh(W),Trabulo(S M),Ra... Oncogene 0000-00-00

...KRAS wild-type normal pancreas cells, as well as in KRAS mutated pancreatic cancer cells and was essential for ER homoeo...

Zhu(W),Gliddon(B L),Jarman(K E),Moretti(P ... Oncogene 0000-00-00

...KRas. Consistent with this, we found that ectopic expression of oncogenic KRas and HRas in cells resulted in elevated CI...

Sefrioui(David),Mauger(Florence),Leclere(L... Clin Chim Acta 0000-00-00

...KRAS mutations in ccfDNA from metastatic colorectal cancer patients by E-ice-COLD-PCR with two digital PCR approaches. F...

Nordmann(Thierry M),Juengling(Freimut D),R... Blood 0000-00-00

...KRAS mutation, without the presence of BRAF Accordingly, the addition of MEK-inhibiting trametinib to BRAF-inhibiting da...

Liu(Xin),Pitarresi(Jason R),Cuitiño(Maria ... Genes Dev 0000-00-00

...Kras-driven pancreatic cancer progression, is currently unclear. Here we show that disruption of paracrine Hedgehog sign...

Queralt(Bernardo),Cuyàs(Elisabet),Bosch-Ba... Oncotarget 0000-00-00

KRAS mutations are an established predictor of lack of response to EGFR-targeted therapies in patients with metastatic c...

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