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SIRT2 deletion enhances KRAS-induced tumorigenesis in vivo by regulating K147...

Song(Ha Yong),Biancucci(Marco),Kang(Hong-J... Oncotarget 0000-00-00

...KRAS activity threshold, along with the finding that only a small percentage of cellsharboring KRAS mutations are transf...

Methylation of MGMT Is Associated with Poor Prognosis in Patients with Stage ...

Fu(Tao),Sharmab(Anup),Xie(Fei),Liu(Yanlian... PLoS One 0000-00-00

...KRAS mutations.,MGMT methylation was detected in 17 of 64 (26.6%) patients, and was not correlated with sex, age, tumor ...

Inhibition of acetyl-CoA carboxylase suppresses fatty acid synthesis and tumo...

Svensson(Robert U),Parker(Seth J),Eichner(... Nat Med 0000-00-00

...Kras;Trp53 (also known as KRAS p53) and Kras;Stk11 (also known as KRAS Lkb1) mouse models of NSCLC. These findings demon...

Somatic mutation analysis of KRAS, BRAF, HER2 and PTEN in EGFR mutation-negat...

Bhaumik(Sangeet),Ahmad(Firoz),Das(Bibhu Ra... Med Oncol 0000-00-00

...KRAS, BRAF, HER2, PTEN mutation in Indian non-small cell lung carcinoma patients. The frequency of KRAS, BRAF, HER2, PTE...

Mutation analysis of circulating plasma DNA to determine response to EGFR tyr...

Riediger(Anja Lisa),Dietz(Steffen),Schirme... Sci Rep 0000-00-00

...KRAS mutations in circulating DNA by digital PCR. Mutant DNA levels were compared with the courses of responses to treat...

α-Mangostin-encapsulated PLGA nanoparticles inhibit pancreatic carcinogenesis...

Verma(Raj Kumar),Yu(Wei),Shrivastava(Anju)... Sci Rep 0000-00-00

...Kras(G12D)) pancreatic CSC characteristics in vitro, and pancreatic carcinogenesis in KPC (Pdx(Cre);LSLKras(G12D);LSL-Tr...

Oncogenic function and clinical implications of SLC3A2-NRG1 fusion in invasiv...

Shin(Dong Hoon),Lee(Donghoon),Hong(Dong Wa... Oncotarget 0000-00-00

...KRAS codon 12 mutations were found in 10 cases. We also found concurrent NRAS Q61L mutation and EML4-ALK fusion in addit...

Mutational landscape of combined hepatocellular carcinoma and cholangiocarcin...

Sasaki(Motoko),Sato(Yasunori),Nakanuma(Yas... Histopathology 0000-00-00

...KRAS, IDH1 or IDH2 (IDH1/2), ARID1A, the TERT promoter, and TP53, and their relationships with clinicopathological featu...

Recurrent mutations of MAPK pathway genes in multiple myeloma but not in amyl...

Kim(Seok Jin),Shin(Hyun-Tae),Lee(Hae-Ock),... Oncotarget 0000-00-00

...KRAS (26%, 6/23) and BRAF (22%, 5/23). However, no significant mutations were found in the 12 patients with AL amyloidos...

Clinical implications of routine genomic mutation sequencing in PIK3CA/AKT1 a...

Cejalvo(Juan Miguel),Pérez-Fidalgo(J Aleja... Breast Cancer Res Treat 0000-00-00

...KRAS, NRAS, and BRAF in order to select patients for targeted therapy clinical trials. The genomes of archived samples o...

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