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TP53 BRCA1 CRISPR single-cell cancer

Boeck(S H),Vehling-Kaiser(U),Waldschmidt(D... J Clin Oncol 0000-00-00

...KRAS mutation (mut). Pts with KRAS wildtype (wt, n=53) had an improved OS (wt: 8.0 mo vs. mut: 6.6 mo; HR 1.62, p=0.011)...

Goss(G D),Lorimer(I),Tsao(M S),O'Callaghan... J Clin Oncol 0000-00-00

...KRAS and EGFR copy are available on 350 and 348 pts respectively. KRAS mutations were neither prognostic HR 1.12 (95% C....

Mitchell(E P),Lacouture(M),Shearer(H),Iann... J Clin Oncol 0000-00-00

...KRAS evaluable pts, 49 (56%) pts had WT KRAS and 38 (44%) pts had MT KRAS. Efficacy and safety are shown. Mean (SD) chan...

Mitsudomi(T),Onozato(R),Kosaka(T),Yatabe(Y... J Clin Oncol 0000-00-00

...KRAS gene and transmembrare region of the MET in a cohort of 211 lung adenocarcinoma. In addition, we searched for mutat...

Darwish(S),Ludovini(V),Pistola(L),Bianconi... J Clin Oncol 0000-00-00

...KRAS, PIK3CA gene mutations in pts with advanced NSCLC who had been treated with gefitinib or erlotinib after failure of...

Král(J),Slyšková(J),Vodička(P),Špičák(J) Klin Onkol 0000-00-00

...KRAS, MMR, microRNA, CIMP etc.). Knowledge of the molecular pathogenesis of CRC (hereditary, sporadic) is crucial for tr...

Rother(J),Bailey(J),Alvarado(G),Prieto(V G... J Clin Oncol 0000-00-00

...KRAS and NRAS (exons 1 and 2) were assessed by quantitative pyrosequencing. MAPK levels were assessed by immunohistochem...

Tan(Mingjia),Xu(Jie),Siddiqui(Javed),Feng(... Mol Cancer 0000-00-00

...Kras to promote lung tumorigenesis, but antagonized Kras to inhibit skin tumorigenesis, suggesting a tissue/context depe...

Kirtane(Tejas),Bhutani(Manoop S) Asian Pac J Trop Med 0000-00-00

...KRAS and GNAS hold promise, but which molecular marker or a combination of markers is most useful and cost effective rem...

Szutowicz-Zielińska(Ewa),Konopa(Krzysztof)... Oncotarget 0000-00-00

...KRAS and BRAF mutations are additionally presented.,This trial argues against using high gene copy number for selection ...

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