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Dynamic landscape of pancreatic carcinogenesis reveals early molecular networ...

Kong(Bo),Bruns(Philipp),Behler(Nora A),Cha... Gut 0000-00-00

...Kras and inflammation has been shown to induce malignancy, molecular networks of early carcinogenesis remain poorly defi...

Pulmonary Kirsten Rat Sarcoma Virus Mutation Positive Mucinous Adenocarcinoma...

Singh(Gopal),Coffey(Amy),Neely(Robert),Lam... Ann Thorac Surg 0000-00-00

...KRAS) mutation positive mucinous adenocarcinoma of the lung (AC) in association with mixed CPAM type 1 and 2. This case ...

Targeting KRas-dependent tumour growth, circulating tumour cells and metastas...

Seviour(E G),Sehgal(V),Mishra(D),Rupaimool... Oncogene 0000-00-00

KRas is mutated in a significant number of human cancers and so there is an urgent therapeutic need to target KRas signa...

Overexpression of microRNA-1288 in oesophageal squamous cell carcinoma.

Gopalan(Vinod),Islam(Farhadul),Pillai(Suja... Exp Cell Res 0000-00-00

...kRAS was examined using immunofluorescence and western blot.,Overexpression of miR-1288 was more often noted in ESCC tis...

Gastrointestinal stromal tumors (GISTs) and second malignancies: A novel "sen...

Rodriquenz(Maria Grazia),Rossi(Sabrina),Ri... Medicine (Baltimore) 0000-00-00

...KRAS mutation in many tumors' pathogenesis, analysis of KRAS was performed in patients with also second neoplasms.Forty-...

Identification of Stem Cells in the Epithelium of the Stomach Corpus and Antr...

Matsuo(Junichi),Kimura(Shunichi),Yamamura(... Gastroenterology 0000-00-00

...KrasG12D/+ mice; gastric tissues were collected and analyzed by histology and immunofluorescence.,Most proliferation occ...

Inhibition of RAF1 kinase activity restores apicobasal polarity and impairs t...

Borovski(Tijana),Vellinga(Thomas T),Laouki... Gut 0000-00-00

...KRAS (∼40%). Here we investigated the role of RAF1 in CRC, as a potential, novel target.,Colonosphere cultures were esta...

High selective pressure for Notch1 mutations that induce Myc in T-cell acute ...

Chiang(Mark Y),Wang(Qing),Gormley(Anna C),... Blood 0000-00-00

...Kras mice transduced with Myc developed T-ALLs that were GSI-insensitive and lacked Notch1 mutations. In contrast, Kras ...

[Prognostic biomarkers for metastatic colorectal cancer].

Neumann(J H L) Pathologe 0000-00-00

...KRAS and BRAF mutations) in combination with a low beta catenin expression could be detected. It can be concluded from t...

The COMET Open-label Phase II Study of Neoadjuvant FOLFOX or XELOX Treatment ...

Kataoka(Masato),Kanda(Mitsuro),Ishigure(Ki... Ann Surg Oncol 0000-00-00

...KRAS group were significantly reduced compared with those of the mutant KRAS group. The overall rates of liver resection...

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